Lung Screening Study

Status Completed

Clinical Trial Summary

RATIONALE: New imaging procedures such as spiral CT may improve the ability to detect lung cancer in patients who are at high risk for the disease.

PURPOSE: Randomized clinical trial to compare the effectiveness of a spiral CT scan with that of a chest x-ray in detecting lung cancer in patients who are at high risk for the disease.

Clinical Trial Description

OBJECTIVES: I. Compare the efficacy of screening spiral CT scan and screening chest x-ray in detecting lung cancer in current or former smokers at high risk for lung cancer.

OUTLINE: This is a randomized, multicenter study of lung cancer screening. Patients are randomized to one of two screening arms. Arm I: Patients undergo one spiral CT scan. Arm II: Patients undergo one chest x-ray. Patients and their primary care physicians are notified of test results within 3 weeks of the exam.

PROJECTED ACCRUAL: A total of 3,000 participants (1,500 per screening arm) will be accrued for this study at six screening centers (500 per center) by October 31, 2000. ;

Study Design

Primary Purpose: Screening

Related Conditions & MeSH terms

Lung Cancer

Clinical Trial Details

NCT number	NCT00006382
Study type	Interventional
Source	National Cancer Institute (NCI)
Contact
Status	Completed
Phase	N/A
Start date	August 2000
Completion date	December 2002

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