Lung Cancer Clinical Trial
Official title:
Whole-Body 18F-Fluorodeoxyglucose Positron Emission Tomography to Measure the Response to Induction Chemotherapy of Potentially Resectable Lung and Esophageal Carcinomas
Verified date | January 2013 |
Source | Memorial Sloan Kettering Cancer Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
RATIONALE: Imaging procedures, such as fludeoxyglucose F 18 positron emission tomography
(PET) scans, may improve the ability to detect lung and esophageal cancer or their
recurrence.
PURPOSE: Phase II/III trial to study the effectiveness of fludeoxyglucose F 18 PET scans in
measuring response to induction chemotherapy in patients with esophageal and lung cancer
that may be removed by surgery.
Status | Completed |
Enrollment | 75 |
Est. completion date | |
Est. primary completion date | October 2002 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
DISEASE CHARACTERISTICS: Histologically confirmed esophageal or non-small cell lung
carcinoma Esophageal cancer: Biopsy proven esophageal carcinoma considered acceptable for
curative esophageal resection Lung cancer: Stages IA-IIIB, T(any)N(any)M0 disease without
pleural effusion, which constitutes locally advanced lung cancer Must be candidates for
induction chemotherapy followed by surgical resection PATIENT CHARACTERISTICS: Age: 18 and over Performance status: Karnofsky 70-100% Life expectancy: Not specified Hematopoietic: WBC at least 4,000/mm3 Platelet count at least 160,000/mm3 Hepatic: Bilirubin no greater than 1.0 mg/dL Renal: Creatinine no greater than 1.5 mg/dL Creatinine clearance greater than 65 mL/min Other: Not pregnant Adequate contraception required of all fertile female patients PRIOR CONCURRENT THERAPY: Biologic therapy: Not specified Chemotherapy: See Disease Characteristics Endocrine therapy: Not specified Radiotherapy: Not specified Surgery: No prior surgical mediastinal staging such as prior mediastinoscopy or Chamberlain procedures See Disease Characteristics |
Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
United States | Memorial Sloan-Kettering Cancer Center | New York | New York |
Lead Sponsor | Collaborator |
---|---|
Memorial Sloan Kettering Cancer Center | National Cancer Institute (NCI) |
United States,
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