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Lung Cancer clinical trials

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NCT ID: NCT04568564 Recruiting - Lung Cancer Clinical Trials

Telerehabilitation in Lung Surgery Patients

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

In this study, providing access to physiotherapy applications by telerehabilitation method and the effectiveness of this application will be examined for patients who have undergone lung surgery in the early postoperative period during the pandemic process in which social isolation continues.

NCT ID: NCT04568291 Recruiting - Lung Cancer Clinical Trials

CTC in Lung Caner Patients With Bone Metastases

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

1. Evaluate the feasibility of single cell sequencing technology based on three-dimensional bionic capture network; 2. To build a risk prediction model of bone related events based on single cell sequencing; 3. To verify the risk prediction model of bone related events by single cell sequencing; 4. To verify the comprehensive treatment of non-small cell lung cancer ( NSCLC) bone metastases.

NCT ID: NCT04567251 Recruiting - Lung Cancer Clinical Trials

Survivorship Study of Cancer Patients Who Received Cranial Radiation Therapy

SPiRiT
Start date: December 28, 2021
Phase:
Study type: Observational

This study represents a survivorship protocol that focuses on cognition and health-related quality of life (HRQoL) in cancer patients that have received prior brain irradiation. The primary purpose of this study is to assess the feasibility of using a digital symptom tracking application focused on HRQoL and cognition in cancer survivors who received brain irradiation.

NCT ID: NCT04563234 Withdrawn - Lung Cancer Clinical Trials

Perioperative Cognitive Training in Thoracic Surgery

COFLEX-T
Start date: June 30, 2023
Phase: N/A
Study type: Interventional

More than 30% of patients undergoing thoracic surgical procedures develop persistent post-surgical pain (PPSP), which results in impaired functioning, diminished quality of life, and increased risk of chronic opioid use. The proposed project aims to determine whether a prospective, randomized, controlled study of smartphone-based perioperative cognitive flexibility training will reduce the incidence of PPSP in high-risk individuals undergoing thoracic surgery.

NCT ID: NCT04558255 Recruiting - Lung Cancer Clinical Trials

A Preliminary Study on the Detection of Plasma Markers in Early Diagnosis for Lung Cancer

Start date: January 1, 2020
Phase:
Study type: Observational

Lung cancer is the most common cancer with the highest morbidity and mortality in the world. Stagement is closely related to the 5 years of survival rate of patients. The postoperative 5-year survival rate is above 90% for stage ⅠA lung cancer patients, while the 5-year survival rate of stage IV lung cancer patients is less than 5%. Therefore, early screening and diagnosis for lung cancer is a key method to reduce lung cancer mortality and prolong survival for patients. At present, low-dose computed tomography (LDCT) is the most effective method for early detection of lung cancer. In addition to imaging examination, plasma tumor markers detection is also a common clinical detection method for tumor screening and postoperative monitoring. Liquid biopsy is a non-invasive or minimally invasive method for testing blood or other liquid samples to analyze tumor-related markers including nucleic acids and proteins. Several studies have explored the detection of hot spot gene mutations, methylation and methylation changes of DNA, protein markers and autoantibodies in peripheral blood in lung cancer patients. Liquid biopsy has generally become the most popular field for early diagnosis of lung cancer. Based above, it is necessary to combine multi-omics methods to improve the detection of early stage lung cancer. In our study, we intend to integrate molecular features obtained through liquid biopsy and clinical data of lung cancer patients, and develop and prospectively validate a machine-learning method which can robustly discriminate early-stage lung cancer patients from controls.

NCT ID: NCT04556435 Terminated - Lung Cancer Clinical Trials

Breath Analysis in Early Stage Lung Cancer Using Infrared Spectroscopy

Start date: February 25, 2021
Phase:
Study type: Observational

The aim of this study is to sample and analyze volatile organic compounds (VOCs) from lung cancer patients and individuals without lung cancer ("healthy" controls). The breath sample analysis will help investigators describe and identify profiles of VOCs found in the breath of patients with lung cancer when compared to normal breath profiles using infrared spectroscopy. This work will help validate early proof of concept results conducted with prototype technology and later stage NSCLC breath samples, and inform future breath testing analysis.

NCT ID: NCT04555564 Withdrawn - Lung Cancer Clinical Trials

Tc99m Macroaggregated Albumin Bronchial Artery Study

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

This is a single-arm, single-center, prospective pilot study to perform bronchial artery Tc-99m-MAA infusion to determine the predicted whole lung versus lung tumor dosimetry of a possible intra-arterial radioembolization.

NCT ID: NCT04553809 Recruiting - Lung Cancer Clinical Trials

Navigation Endobronchial Ultrasound

NEBULA
Start date: October 12, 2020
Phase: N/A
Study type: Interventional

Lung cancer is the primary cause of cancer related deaths in Denmark. In order to improve the prognosis diagnosis in earlier stages are needed. This will however require improved sampling techniques from very small lung lesions. One method involves the use of a radial ultrasound probe inserted in the working channel of the bronchoscope, to more accurately identify the lung lesions before sampling them (rEBUS). The other method involves the use of electromagnetic navigation bronchoscopy (ENB) to guide the operator to the lung lesion. This study aims to determine whether a combination of rEBUS and ENB is superior to ENB alone in biopsy sampling. The study will be conducted as a non-blinded RCT. Furthermore, we will make an estimate of the hospital costs of the entire diagnostic work up for lung cancer when combining ENB and rEBUS compared to ENB alone.

NCT ID: NCT04552054 Recruiting - Lung Cancer Clinical Trials

Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules

MR&3D Local
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

This study evaluates the viability and accuracy of preoperative mixed reality technique combined with three-dimensional printing navigational template guided localizing pulmonary small nodules.

NCT ID: NCT04548830 Active, not recruiting - Lung Cancer Clinical Trials

Safety of Lung Cryobiopsy in People With Cancer

Start date: September 8, 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out whether a biopsy technique called transbronchial cryobiopsy (TBCB) is a safe alternative to the standard biopsy procedure (transbronchial forceps biopsy; TBFB). The study researchers think that TBCB may provide better biopsy samples to help diagnose lung disease.