Lung Cancer Stage I Clinical Trial
Official title:
Clinical Application of Vagus Nerve Preservation in Minimally Invasive Surgery for Early Lung Cancer
Through prospective, randomized and controlled clinical study, patients with early lung cancer who do not need lymph node dissection according to routine diagnosis and treatment were selected. The feasibility and safety of preserving vagal pulmonary branch intact during minimally invasive surgery were compared with traditional minimally invasive surgery, and the feasibility and safety of preserving vagal pulmonary branch intact during minimally invasive surgery were clarified. The effect of preserving pulmonary branches of vagus nerve in minimally invasive surgery of early lung cancer on preventing or reducing pulmonary complications after operation was evaluated by main observation indexes (incidence of pulmonary complications) and secondary evaluation indexes. It will provide a safer, simpler and more effective new technology for patients with early lung cancer undergoing minimally invasive surgery, and provide a basis for the popularization of this new technology.
According to the suggestion of statistical experts and the minimum sample size, 120 IA1-2 patients who are going to undergo thoracoscopic lung surgery were selected according to the criteria of admission and exclusion. The risk and benefit were informed and the informed consent of the subjects was signed. The patients were numbered and randomly divided into two groups: group A with vagus nerve preservation during minimally invasive surgery and group B with traditional minimally invasive surgery for early lung cancer. The incidence of pulmonary complications within 5 weeks after operation (see the evaluation criteria for details), operation time, intraoperative bleeding volume, postoperative drainage volume, postoperative mortality, incidence of cardiovascular complications, rate of re-tracheal intubation, rate of re-admission to ICU, duration of stay in ICU, hospitalization costs were observed. Statistical analysis and evaluation of the safety of preserving pulmonary branches of vagus nerve in minimally invasive surgery and the effectiveness of preventing or reducing pulmonary complications after minimally invasive surgery. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT04375566 -
Progressive Web App About Individualized Patient Decision Aid for NSCLC Stage I-II
|
||
| Not yet recruiting |
NCT06060964 -
Enabling Remote Access to Breathe Easier: A Novel Approach to Improve Symptom Management
|
Early Phase 1 | |
| Active, not recruiting |
NCT03322072 -
Calypso Guided High Precision Stereotactic Ablative Radiosurgery for Lung TUmours Using Real-Time Tumour Tracking & Respiratory Gating
|
N/A | |
| Recruiting |
NCT06424327 -
A Registry for People With Lung Cancer
|
||
| Recruiting |
NCT03290534 -
Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
|
Phase 2 | |
| Recruiting |
NCT05281237 -
Avecure Flexible Microwave Ablation Probe For Lung Nodules
|
N/A | |
| Recruiting |
NCT06432972 -
Accelerated Pulmonary Rehabilitation in the Preoperative Period
|
N/A | |
| Terminated |
NCT03984019 -
Cardiac Changes After Stereotactic Radiotherapy for Early Stage NSCLC Cancer or Lung Metastasis
|
N/A | |
| Active, not recruiting |
NCT05832112 -
Outside the Cage (OTC) Robotic Lobectomy
|
N/A | |
| Recruiting |
NCT06016881 -
Postoperative Chronic Operation-related Symptoms After Minimally Invasive Lung Surgery
|
||
| Recruiting |
NCT04944173 -
SCION: SABR and Checkpoint Inhibition Of NSCLC
|
Phase 2 |