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Clinical Trial Summary

This study was proposed to validate the efficacy of gefitinib as first-line therapy in advanced lung adenocarcinoma with EGFR mutation determined by plasma cf-DNA.


Clinical Trial Description

Patients without enough tissue for EGFR mutation detection can also have opportunity to use EGFR-TKI as first line therapy. Meanwhile, this study was also proposed to explore the best intervention time of anti-resistant drugs (such as AZD 9291, a T790M inhibitor) through the quantitative and dynamic analysis of EGFR sensitive and resistant mutation in plasma cf-DNA during EGFR-TKI treatment process. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02282267
Study type Interventional
Source Beijing Cancer Hospital
Contact
Status Active, not recruiting
Phase N/A
Start date October 2014
Completion date February 2018

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