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Lumbar Disc Herniation clinical trials

View clinical trials related to Lumbar Disc Herniation.

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NCT ID: NCT03607838 Completed - Clinical trials for Lumbar Disc Herniation

SI-6603 (Condoliase) Study for Lumbar Disc Herniation (Discovery 6603 Study)

Start date: May 30, 2018
Phase: Phase 3
Study type: Interventional

This study is to evaluate the effectiveness of a single-dose intervertebral disc injection of SI-6603 in subjects with lumbar disc herniation (LDH)

NCT ID: NCT03482492 Completed - Clinical trials for Lumbar Disc Herniation

Tramadol vs.Tramadol With Paracetamol

Start date: March 20, 2014
Phase: N/A
Study type: Interventional

This study focused on to determine postoperative analgesic efficacy of tramadol compared to tramadol with addition of paracetamol after a lumbar disc surgery.

NCT ID: NCT03386149 Completed - Clinical trials for Lumbar Disc Herniation

Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine

Start date: December 28, 2017
Phase: Phase 3
Study type: Interventional

This randomized controlled clinical trial is designed to evaluate the efficacy and safety of Bosinji on low back pain and radiating pain of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.

NCT ID: NCT03273036 Completed - Clinical trials for Lumbar Disc Herniation

Perioperative Outcome of Corticosteroids in Transforaminal Endoscopic Lumbar Discectomy

Start date: May 1, 2014
Phase: Phase 4
Study type: Interventional

The endoscopic discectomy has rapidly developed and increased need by patients. This procedure is widely performed by interventional pain physicians as well as by spine surgeons because it requires no general anesthesia or admission to a hospital. Many studies were reported that corticosteroid injection can inhibit persistent postoperative pain in lumbar discectomy. However, data of perioperative epidural steroids after an endoscopic discectomy is lacking.

NCT ID: NCT03236753 Completed - Clinical trials for Lumbar Disc Herniation

Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine

Start date: August 11, 2017
Phase: N/A
Study type: Interventional

This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.

NCT ID: NCT03137485 Completed - Clinical trials for Lumbar Disc Herniation

Comparison Between Conventional vs. Endoscopic Lumbar Discectomy

Start date: December 2016
Phase: N/A
Study type: Interventional

This study is aimed to compare between the results of conventional lumbar discectomy and the newly used technique in our department; endoscopic lumbar discectomy in neurosurgery department Assiut university hospitals, so that we can offer our patients the best service in an updated and minimally invasive way.

NCT ID: NCT02836730 Completed - Clinical trials for Lumbar Spinal Stenosis

Long-term Outcomes of Surgical and Nonsurgical Management of Sciatica Secondary to a Lumbar Disc Herniation or Spinal Stenosis

Start date: November 2004
Phase: N/A
Study type: Observational

The rate of success 12 months after surgery is reported to be 60-65% in patients with lumbar disc herniation and 60-70% in patients with spinal stenosis. At the Back Center Copenhagen, patients with persistent low back pain caused by lumbar disc herniation and spinal stenosis are treated by a multidisciplinary team comprising rheumatologists, physiotherapists, chiropractors, and social workers according to current guidelines. Therefore we have a unique opportunity to report the long term outcome in candidates for surgery, regardless of whether they have surgery or not, after having received optimal but unsuccessful nonsurgical treatment. The purpose of this study is to answer the following questions: 1) What is the proportion of patients operated upon after referral to surgical evaluation with positive MRI findings, persistent low back pain, and poor outcome following non-operative treatment? 2) What was the outcome in these patients 2 years following referral? 3) Where any baseline variables predictive of good or poor postsurgical outcome? 4) Where there any difference in outcome in patients with or without surgery?

NCT ID: NCT02699164 Completed - Clinical trials for Lumbar Disc Herniation

Remission of Lumbar Disc Herniation by Physiotherapy

Start date: January 2014
Phase: N/A
Study type: Interventional

This study was conducted with the aim of determining whether or not Non surgical spinal decompression therapy was effective in remission of herniation, decreasing pain and improving functional status.

NCT ID: NCT02572622 Completed - Clinical trials for Lumbar Disc Herniation

Comparison of Different Treatment Methods in Lumbal Disc Herniation Treatment

Start date: February 2014
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effectiveness of three different treatment methods which consists spinal decompression, deep friction massage and exercise. The patients were separated three groups Group one received non-surgical spinal decompression therapy, group two received non-surgical spinal decompression, lumbar stabilization exercises and manual therapy, group three received manual therapy and lumbar stabilization exercises. All groups completed 15 sessions of therapy. In each session, pain severity was assessed with numeric analog scale, straight leg raise test applied and the degree of the hip flexion where the patient reported pain were recorded, respectively. Static, dynamic muscle strength-endurance tests were applied before the treatment sessions started, after the treatment sessions ended, six weeks after and three months after the study. Oswestry Disability Scale (ODI), Back Performance Scale (BPS), Lanss Neuropathic pain Questionnaire, Fear-Avoidance-Beliefs Questionnaire (FABQ) and McGill Pain Questionnaire were applied before the treatment sessions started, after the treatment sessions ended and three months after the study. Gradient of disc height and thickness of the herniation were assessed segmentally with magnetic resonance imagination (MRI) before the study and three months after the study.

NCT ID: NCT01978912 Completed - Clinical trials for Lumbar Disc Herniation

A Study to Evaluate Safety and Exploratory Efficacy of KTP-001 in Subjects With Lumbar Disc Herniation

Start date: February 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and exploratory efficacy of KTP-001 in subjects with lumbar disc herniation.