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Assessment of LTP-like Pain Amplification in Chronic Low Back Pain Patients

Low Back Pain Clinical Trial

Official title:
Assessment of Long-term Potentiation (LTP)-Like Pain Amplification in Chronic Low Back Pain Patients

Clinical Trial Summary

The present study is aimed to assess the LTP-like pain amplification in chronic low back pain patients to explore the central and peripheral effect for pain LTP.

Clinical Trial Description

This study is a cross-sectional study. Two groups, including low back pain group and healthy subjects group will be arranged in this study. 50 subjects will be recruited in each group, The healthy subjects were matched for sex and age in relation to the low back pain group. Conditioning electrical stimulation (100 Hz, repeated 5 times with 10 s intervals, 500 impulses) using circular pin electrodes will be used in both groups to induce LTP-like pain amplification. The pain intensity changes to pinprick and light touch stimuli will be compared between two groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03362827
Study type Observational
Source Peking University People's Hospital
Contact Weiwei Xia, Ph.D.
Phone 008613260001978
Email 523526767@qq.com
Status Not yet recruiting
Phase N/A
Start date March 1, 2018
Completion date December 31, 2018
View Details
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