Liver Tumor Clinical Trial
Official title:
Practical Application of Indocyanine Green Camera in Laparoscopic Liver Surgery
"Indocyanine Green (ICG) is a dye used as an indicator of hepatic function considering its
capacity to be eliminated only by the bile. Thus, ICG tend to remain in liver tumors.
The hypothesis of CAMVIC study is that the use of fluorescence imaging during laparoscopic
hepatic surgery will allow to detect small subcapsular superficial lesions undetected by
other diagnostic methods, which will improve the results of the oncologic treatment."
"Thanks to the property of ICG to release a fluorescent signal when excited by a Near Infra
Red (NIR) light source, ICG fluorescence has been widely used during several clinical
situations (angiography, lymphography,..). Few years ago it has been shown that hepatic
tumors could be seen with a NIR camera able to view ICG fluorescence thanks to the depot in
or around the tumor of the dye injected during preop.Since, this fluorescence imaging
technique potential has been underlined to identify tumors undiagnosed before surgery.
Pre-operative examination of hepatic lesions is based on 3 points:
- visual examination
- two-hand palpation
- intra-operative ultrasound.
During laparoscopic hepatic surgery it is not possible to palpate the liver thus peroperative
examination of the liver surface is harder than during open surgery. Moreover per-operative
ultrasound is not a reliable tool in order to explore liver surface. However the latest
development of NIR cameras able to view ICG fluorescence could add a benefit in laparoscopic
surgery in view of its capacity to detect superficial lesions, even those of small
dimension."
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