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Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant Recipients

Liver Transplant; Complications Clinical Trial

Official title:
Correlation of Blood Gene Expression (TruGraf Liver) With Liver Biopsy in Pediatric Liver Transplant Recipients

Clinical Trial Summary

Liver transplant rejection is when the body's immune system attacks and damages the liver of a transplant recipient. Currently the best way to see if that is happening is with a liver biopsy. The purpose of this research study is to see if a simple blood test can diagnose if a transplanted liver is being rejected.

Clinical Trial Description

This study is an investigator-initiated, prospective, single-cohort trial to assess the ability of the TruGraf® Liver gene expression panel (GEP) to predict rejection in pediatric liver transplant recipients undergoing surveillance and for-cause liver biopsy. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06263114
Study type Observational
Source Children's Mercy Hospital Kansas City
Contact Corey Schurman, MA
Phone 8163023076
Email crschurman@cmh.edu
Status Recruiting
Phase
Start date January 1, 2024
Completion date January 1, 2027
View Details
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