Glycocalyx During Normothermic Machine Perfusion

Status Completed

Clinical Trial Summary

An organ intended for transplantation is normally stored on ice (cold storage, CS) after explantation from the donor. During this storage process, damage to the endothelial glycocalyx occurs. It is known from numerous studies that the integrity of the endothelial glycocalyx is necessary for organ function. Normothermic machine perfusion is an alternative storage method for explanted livers, where the graft is perfused with warm blood. This study aims to clarify the influence of normothermic machine perfusion on endothelial glycocalyx damage of the graft.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04764266
Study type	Interventional
Source	Medical University Innsbruck
Contact
Status	Completed
Phase	N/A
Start date	February 10, 2021
Completion date	February 1, 2024

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