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Liver Resection clinical trials

View clinical trials related to Liver Resection.

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NCT ID: NCT02031094 Completed - Liver Resection Clinical Trials

Energy Expenditure and Regeneration Following Liver Resection Resection

EAGLE
Start date: January 2014
Phase: N/A
Study type: Observational

This observational study will measure resting energy expenditure in patients who have undergone liver resection and compare methods of measuring resting energy expenditure.

NCT ID: NCT01960049 Completed - Postoperative Pain Clinical Trials

Novel Technique of Analgesia Following Open Liver Resection

Start date: October 2013
Phase: Phase 4
Study type: Interventional

Abdominal wall incisions used for liver surgeries are associated with significant postoperative pain and disability. Epidural analgesia is often contraindicated in these patients due to common bleeding problems. Furthermore, drugs such as acetaminophen and opioids are often inadequate and can lead to detrimental side-effects. Abdominal wall (AW) catheters can be placed during surgical closure along the incision line and can be used to administer local anesthetics for postoperative pain. The study is a multi-centre, double-blind, randomized controlled trial involving 120 patients undergoing elective liver surgery. Patients will be randomly assigned to AW catheter group treated with drug or control treated with saline. Treatment group will receive AW catheters with ropivacaine plus standard patient controlled analgesia (PCA). Control group will obtain AW with normal saline and no local anesthetics and PCA. Patients are followed for 6 months post-operatively for pain scores, side-effects, chronic pain and complications.

NCT ID: NCT01921985 Terminated - Liver Failure Clinical Trials

Terlipressin Administration in Patients Undergoing Major Liver Resection

Start date: November 2013
Phase: Phase 2
Study type: Interventional

This study investigates if the administration of terlipressin reduces complications after major liver surgery.

NCT ID: NCT01858987 Completed - Liver Resection Clinical Trials

Stapler vs. LigaSure in Elective Hepatic Resection

CRUNSHII
Start date: November 2, 2011
Phase: N/A
Study type: Interventional

The optimal technique of parenchymal transection in liver surgery has remained a matter of controversial debate among hepatobiliary surgeons. The optimal technique should enable secure sealing of the vascular and biliary structures that results in low intraoperative blood loss as well as low postoperative complication rates. Although numerous devices have been introduced and are used widely, high-level evidence, randomized controlled trials, that evaluate efficacy and safety of these devices are scarce. In the present randomized controlled trial two techniques of hepatic resection using vascular staplers and the LigaSure vessel sealing device are compared. While the primary endpoint is intraoperative blood loss a set of general and surgical variables will be analyzed to evaluate efficacy and safety of both methods.

NCT ID: NCT01770041 Completed - Liver Resection Clinical Trials

Paracetamol Metabolism After Liver Surgery

PETALS
Start date: February 2013
Phase: N/A
Study type: Observational

This observational study will assess the metabolic pathways of paracetamol that are utilised after liver resection.

NCT ID: NCT01355887 Recruiting - Liver Resection Clinical Trials

A Trial to Compare Pringle Maneuver With Either Infrahepatic Inferior Vena Cava Clamping or Low Central Venous Pressure

Start date: January 2008
Phase: Phase 3
Study type: Observational

The purpose of this study is to better comprehend the benefits and efficacy of portal triad clamping with infrahepatic IVC clamping during complex hepatectomy. A randomized comparative trial was performed to compare PTC(pringle triad clamping) with either infrahepatic IVC clamping or low central venous pressure in complex liver resections.