Impact of Blood Salvage Therapy on Outcomes After Oncologic Liver Surgery

Status Completed

Clinical Trial Summary

A before and after trial comparing the systematic use of blood salvage therapy with leucocyte filter during oncologic liver resections. Recurrence, survival, allogenic transfusion rates and surgical outcomes are compared with a representative historic cohort.

Clinical Trial Description

Blood salvage therapy in oncologic liver surgery is seldom used based on unproven concerns about the safety of the technique regarding potential cancer dissemination or recurrence. Nevertheless, the technique has proven advantages in other surgical settings regarding the allogenic transfusion outcomes. Allogenic blood transfusion has been scientifically proven to worsen prognosis in oncologic surgery. This study compares a cohort of patients systematically exposed the blood salvage therapy to one comparable cohort without the therapy and outcomes regarding transfusion rates, post-operative Hb measurement, recurrence, overall survival, and post-operative adverse events. ;

Study Design

Related Conditions & MeSH terms

Liver Neoplasms

Clinical Trial Details

NCT number	NCT05164406
Study type	Observational
Source	Université de Sherbrooke
Contact
Status	Completed
Phase
Start date	January 1, 2018
Completion date	February 28, 2021

View Details

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