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NCT03577067 Clinical Trial

Complicated Outcome Prediction After Liver Resection

Liver Neoplasms Clinical Trial

Official title:
Complicated Outcome Prediction After Liver Resection: the Role of Renal Resistive Index

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03577067
Other study ID # CE Humanitas 100/15
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 2015
Est. completion date March 2017

Study information
Verified date July 2018
Source University of Milan
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Although mortality after liver surgery reduced during the last three decades to less than 2%, post-operative course is still complicated in a range of 20-50% of cases.The identification of one or few factors which could detect the real risk of complicated post-operative outcome, may help anesthesiologist to decide whether admit a patient to ICU or not.The primary aim of this study was to evaluate whether RRI, alone or along with other items, can predict post-operative complication after hepatic resection.

Recruitment information / eligibility
Status Completed
Enrollment 183
Est. completion date March 2017
Est. primary completion date March 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

Patients resectable and affected by primary and secondary liver disease

Exclusion Criteria:

Subjects affected by kidney disease and/or cirrhosis and pregnant patients were excluded from the trial. Patients who should have needed nephrectomy during the operation would be also excluded.

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Liver resection for primary and secondary disease
Liver resection in parenchyma-sparing setting for primary and secondary disease

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University of Milan

Outcome
Type Measure Description Time frame Safety issue
Primary renal resistive index (RRI) the association between RRI and occurrence of hepatic complications during the first postoperative week. up to 7 days after surgery
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