Liver Neoplasms Clinical Trial
Official title:
Contrast Sonography for Evaluation of Liver Tumors Prior to Radiofrequency Ablation
The purpose of this study is to determine the efficacy of the Definity (perflutren lipid
microsphere Injectable Suspension) ultrasound contrast agent in identifying small tumors
(hepatomas & metastases) within the liver.
Primary objective: To estimate the increase in conspicuity of small intrahepatic tumors with
contrast-enhanced sonography
Secondary Objectives: To estimate the effect of tumor type, size, location and depth on the
conspicuity of small tumors on contrast-enhanced sonography
An estimated 75 patients (age 18 years of age or older) will be enrolled from the population of patients who present for ultrasound-guided radiofrequency ablation (RFA) of CT or MRI-confirmed multiple primary hepatocellular carcinoma (HCC) or metastatic carcinoma, with at least one of the tumors being ≤ 1.5 cm in diameter. ;
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