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NCT05264051 Clinical Trial

MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease

Liver Diseases Clinical Trial

Official title:
MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05264051
Other study ID # IRB21-0900
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date April 18, 2022
Est. completion date March 1, 2027

Study information
Verified date April 2023
Source University of Chicago
Contact Omar Jamil, MD
Phone 847-373-2360
Email Omar.Jamil@uchospitals.edu
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of the study is to study the muscle assessment score (MAsS, utilizing MRI, as an objective measure of frailty and muscle composition to serve as a predictor of morbidity and mortality in patients with liver disease.

Description:

Prospective study of patients seen at the Univ. of Chicago Medical Center hospital and ambulatory clinics. The assessment of the MAsS score will require an additional 8-10 minutes in the MRI for each patient already undergoing MRI exam. Four groups of pts. who are already scheduled for MRI for routine clinical purposes will be evaluated. 1. Pts. hospitalized with acute hepatic decompensation for whom MRI is otherwise indicated for clinical evaluation. 2. Pts. with hepatobiliary neoplasia 3. Pts.undergoing transjugular portosystemic shunt (TIPS) placement 4. Pts. with chronic liver disease undergoing magnetic resonance elastography for routine monitoring

Recruitment information / eligibility
Status Recruiting
Enrollment 1200
Est. completion date March 1, 2027
Est. primary completion date March 1, 2027
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Patients who are already scheduled for an MRI for routine clinical purposes will be evaluated Exclusion Criteria: - <18 yrs. of age

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States The University of Chicago Chicago Illinois

Sponsors (1)
Lead Sponsor Collaborator
University of Chicago

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Waitlist Mortality Death prior to liver transplant or delisting from enrollment in the study Measured up to 10 years out from enrollment
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