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Diagnosing Minimal Hepatic Encephalopathy — MindTheLiver  

Liver Cirrhosis Clinical Trial

Official title:
Diagnostik af Minimal Hepatisk Encephalopati: Association Mellem Kontinuert reaktionsstidsmåling og EEG-indices

Clinical Trial Summary

Our purpose is to 1. Examine the correlation between MDF in a resting EEG, recorded just before the CRT test, and the variance in reaction times indicated by the CRT index 2. At simultaneous CRT and EEG recording, examine whether a change in EEG is seen immediately before an extended reaction time occurs (defined by the 75th percentile). This will shed light on a direct pathophysiological association between what is measured with EEG and CRT. 3. Investigate whether cyclicity can be detected in the continuous reaction times and if so, whether amplitude and wavelength in this cyclic activity are correlated to EEG parameters. 4. Examine whether a response to standard HE treatment can be detected with EEG in patients who are thought to suffer from it. As well as if baseline outcome predict future hepatic encephalopathy. 5. With a view to further validating our findings, investigators want to correlate results from EEG and CRT with the most internationally widespread psychometric test, the Portosystemic Encephalopathy test (PSE), which necessitates the establishment of Danish normal values. A secondary purpose of this study is therefore 6. To establish Danish normal values for the PSE test and the Animal Naming test in Danes

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05433948
Study type Observational
Source Hospital of South West Jutland
Contact
Status Enrolling by invitation
Phase
Start date December 1, 2019
Completion date December 1, 2031
View Details
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