Liver Cirrhosis Clinical Trial
Official title:
Associated Balance of Risk Score - Comprehensive Complication Index for the Prediction of Long-term Survival After Liver Transplantation
NCT number | NCT03723317 |
Other study ID # | #0003 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 15, 2018 |
Est. completion date | October 15, 2018 |
Verified date | October 2018 |
Source | European Hepatocellular Cancer Liver Transplant Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
In recent years, several scoring systems have been developed aimed at predicting early
post-LT graft function. However, many of them showed poor efficacy when long-term survivals
were tested. Moreover, the necessity to find an easy-to-use score represents another
obstacle, with several scores composed by numerous, difficult to find, variables. Recently,
the pre-LT Balance of Risk (BAR) and the post-LT Comprehensive Complication Index (CCI) have
been created, but their external validation and integration in this setting is lacking.
This study aims at constructing an easy-to-use score system based on the combination of a
small number of pre- and immediately post-liver transplant (LT) independent variables, in
order to accurately predict long-term graft survival after LT.
Status | Completed |
Enrollment | 1782 |
Est. completion date | October 15, 2018 |
Est. primary completion date | October 15, 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - First transplant - adult (>18 years) Exclusion Criteria: - living donation - re-transplant - combined transplant - domino transplant - paediatric transplant |
Country | Name | City | State |
---|---|---|---|
Belgium | UCL | Brussels |
Lead Sponsor | Collaborator |
---|---|
European Hepatocellular Cancer Liver Transplant Group |
Belgium,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Five-year post-transplant graft survival | Number of participants experiencing a graft loss for any reason | 5 years | |
Secondary | Re-transplant rate | Number of participants experiencing a re-transplant for any reason | 5 years |
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