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NCT01151475 Clinical Trial

Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of Hepatic Encephalopathy (HE)

Liver Cirrhosis Clinical Trial

Official title:
Cerebral Oxygen, Blood Flow and Ammonia Uptake in Patients With Cirrhosis and an Acute Episode of HE

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01151475
Other study ID # 24698
Secondary ID
Status Completed
Phase N/A
First received June 25, 2010
Last updated June 18, 2012
Start date August 2010
Est. completion date August 2011

Study information
Verified date June 2012
Source University of Aarhus
Contact n/a
Is FDA regulated No
Health authority Denmark: Danish Dataprotection Agency
Study type Observational

Clinical Trial Summary

We wish to study patients with liver cirrhosis during and 2 weeks after an acute episode of liver coma (hepatic encephalopathy). By means of Positron Emission Tomography we investigate; brain blood flow, brain ammonia uptake and brain oxygen consumption. We hypothesize that blood flow an oxygen consumption is diminished and ammonia uptake increased during an acute episode of hepatic encephalopathy.

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date August 2011
Est. primary completion date August 2011
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- patients with an acute episode of hepatic encephalopathy

Exclusion Criteria:

- previous stroke

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Denmark Gitte Dam Aarhus

Sponsors (1)
Lead Sponsor Collaborator
University of Aarhus

Country where clinical trial is conducted

Denmark, 

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