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NCT00245310 Clinical Trial

Indocyangreen Elimination in Cirrhosis and Acute Liver Failure

Liver Cirrhosis Clinical Trial

Official title:
Evaluation of the Indocyangreen Elimination as a Prognostic Marker in Decompensated Cirrhosis and Acute Liver Failure

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00245310
Other study ID # LiMON
Secondary ID
Status Completed
Phase N/A
First received October 25, 2005
Last updated October 8, 2010
Start date October 2005
Est. completion date October 2010

Study information
Verified date November 2008
Source Heidelberg University
Contact n/a
Is FDA regulated No
Health authority Germany: Federal Institute for Drugs and Medical Devices
Study type Observational

Clinical Trial Summary

Indocyangreen (ICG)is totally biliary eliminated and corresponds to hepatocyte function and liver perfusion.

The ICG-clearance will be evaluated as a prognostic marker in liver disease.

Description:

patients with acute liver failure or advanced liver disease will be studied. ICG-clearance will be correlated with established clinical scores and outcome.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date October 2010
Est. primary completion date October 2010
Accepts healthy volunteers No
Gender Both
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria:

- acute liver failure OR end-stage liver disease

- normal hepatic perfusion by doppler ultrasound

Exclusion Criteria:

- portal vein thrombosis

- allergy to ICG or iodine

- thyroid disease

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• Indocyangreen (ICG) clearance

Locations
Country Name City State
Germany University of Heidelberg Heidelberg

Sponsors (1)
Lead Sponsor Collaborator
Heidelberg University

Country where clinical trial is conducted

Germany, 

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