Liver Cancer Clinical Trial
— TRANSGISTOfficial title:
Liver Transplantation in Patients With Unresectable GastroIntestinal Stromal Tumors (GIST) Liver Metastases
Verified date | February 2022 |
Source | Hospital Universitario Virgen de la Arrixaca |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Liver Transplantation for Unresectable GIST Liver Metastases
Status | Not yet recruiting |
Enrollment | 50 |
Est. completion date | December 2025 |
Est. primary completion date | December 2023 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - GIST diagnosis (c-Kit, CD34, DOG-1) - Imatinib-sensitive mutation - Non-resectable liver metastases - Abscence of extrahepatic disease - Period greater than two years between primary tumor and metastases diagnosis |
Country | Name | City | State |
---|---|---|---|
Spain | Felipe Alconchel | Murcia |
Lead Sponsor | Collaborator |
---|---|
Hospital Universitario Virgen de la Arrixaca |
Spain,
Fernández JÁ, Alconchel F, Gómez B, Martínez J, Ramírez P. Unresectable GIST liver metastases and liver transplantation: A review and theoretical basis for a new indication. Int J Surg. 2021 Oct;94:106126. doi: 10.1016/j.ijsu.2021.106126. Epub 2021 Sep 27. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Overall Survival | Survival | Through study completion, an average of 2 years | |
Primary | Graft Survival | Liver graft Survival | Through study completion, an average of 2 years | |
Secondary | Relapse free survival | Through study completion, an average of 2 years | ||
Secondary | Disease free survival | Through study completion, an average of 2 years |
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