Liver Cancer Clinical Trial
Official title:
Perspective Evaluation of Hormones Involved in Serum Phosphate Homeostasis in Patients With Metastatic Renal Cells Carcinoma or Hepatocellular Carcinoma Treated With Sorafenib. Multicenter Cohort Study
The study includes the recruitment of patients with advanced renal cells carcinoma and hepatocarcinoma in treatment with sorafenib. Multicenter cohort study. It is a prospective observational study.
Several tyrosin kinase inhibitors are able to induce hypophosphatemia but the mechanisms
underling this metabolic disorder are unknown.
Sorafenib is probably the drug in which this metabolic disturbance is most frequent. The aim
of the study is identify variation of blood serum analites involved in hypophosphatemia in
patients with advanced renal cells carcinoma and hepatocarcinoma in treatment with
sorafenib.
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Observational Model: Cohort, Time Perspective: Prospective
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