Lipoprotein Disorder Clinical Trial
Official title:
Extreme Lipids Repository
This is a prospective, observational study to establish a repository of samples from patients with extreme lipid phenotypes including but not limited to hyperlipidemia, dyslipidemia, hyperlipoproteinemia, extreme low/high HDL levels and deranged lipoprotein metabolism. The investigators plan to conduct sophisticated composition and functional analyses as well as genetic analysis to better understand the determinants of extreme lipid derangements.
Status | Recruiting |
Enrollment | 250 |
Est. completion date | May 2029 |
Est. primary completion date | May 2029 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - adult patients (age 18 years or older) diagnosed with any lipid or metabolic disorder including hyperlipidemia, dyslipidemia, hyperlipoproteinemia, low HDL levels and deranged lipoprotein metabolism Exclusion Criteria: - Anyone under 18 years of age will be excluded from the study. |
Country | Name | City | State |
---|---|---|---|
United States | Parkland Health Hospital System | Dallas | Texas |
United States | University of Texas Southwestern Medical Center - Ambulatory Clinic | Dallas | Texas |
Lead Sponsor | Collaborator |
---|---|
University of Texas Southwestern Medical Center | National Heart, Lung, and Blood Institute (NHLBI) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Biological sample collection for repository | Blood samples will be collected for preparation of plasma and serum, extraction of DNA and isolation of circulating cells. Future analysis include genomic, proteomic and metabolomic analysis | Day 1 | |
Primary | Data collection for repository | Demographic information, clinical history and lipid related bio-marker information will be collected from participants | Day 1 |
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