Lipodystrophy Clinical Trial
Official title:
Respiratory Variation of Carotid Doppler Peak Velocity in Liposuction Fluid Management
This study aims to compare the hemodynamic parameters, postoperative plethysmography variability index, the total amount of postoperative intravenous fluid administration needed, and the urine output of two methods of fluid resuscitation during liposuction surgery. One method involves using carotid artery Doppler peak velocity variation, while the other is the conventional fluid ratio.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | December 2024 |
Est. primary completion date | November 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 21 Years to 60 Years |
Eligibility | Inclusion Criteria: - Female patients between 21 and 60 years old - Liposuction with or without abdominoplasty - American Society of Anesthesiologists ? & ??. Exclusion Criteria: - History of previous liposuction surgery - American Society of Anesthesiologist III - Coagulation disorders - Cardiopulmonary disorders |
Country | Name | City | State |
---|---|---|---|
Mexico | TJ Plast out patient, S.A. de C.V. | Tijuana | Baja California |
Lead Sponsor | Collaborator |
---|---|
TJ Plast Advanced Center for Plastic Surgery |
Mexico,
Ibarra-Estrada MA, Lopez-Pulgarin JA, Mijangos-Mendez JC, Diaz-Gomez JL, Aguirre-Avalos G. Respiratory variation in carotid peak systolic velocity predicts volume responsiveness in mechanically ventilated patients with septic shock: a prospective cohort s — View Citation
Song Y, Kwak YL, Song JW, Kim YJ, Shim JK. Respirophasic carotid artery peak velocity variation as a predictor of fluid responsiveness in mechanically ventilated patients with coronary artery disease. Br J Anaesth. 2014 Jul;113(1):61-6. doi: 10.1093/bja/a — View Citation
Wang G, Cao WG, Zhao TL. Fluid management in extensive liposuction: A retrospective review of 83 consecutive patients. Medicine (Baltimore). 2018 Oct;97(41):e12655. doi: 10.1097/MD.0000000000012655. Erratum In: Medicine (Baltimore). 2018 Nov;97(44):e13212. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mean Postoperative PVi | Following surgery, patients will be hospitalized for 24 hours. Throughout this period, the investigators will keep a close eye on the Plethysmography Variability Index (PVi) in both groups. The PVi is a dynamic index that measures the relative variability of the plethysmography waveform detected noninvasively from a pulse oximetry sensor, ranging from 0 to 100. By automatically calculating the dynamic changes that occur during the respiratory cycle, it uses the detected amplitudes. A higher variability in the plethysmography waveform has been linked to preload dependence and fluid responders. If the PVi exceeds 15%, the patient will receive a fluid bolus of lactated ringer solution at a rate of 4-6 ml/kg over 10-15 minutes. | 24 hours | |
Primary | Postoperative intravenous fluid balance | Following surgery, patients will be hospitalized for 24 hours. During the postoperative period, the investigators will keep track and document the exact volume of fluid administered in milliliters. | 24 hours | |
Secondary | The intraoperative total volume of urine in the patient's catheter bag | During the intraoperative period, the investigators will measure and record the total volume of urine accumulated in the patient's catheter bag over the surgery period and will report urine output measured in milliliters per kilogram per hour. | the duration of the surgery | |
Secondary | The postoperative total volume of urine in the patient's catheter bag | During the postoperative period, the investigators will measure and record the total volume of urine accumulated in the patient's catheter bag over a 24-hour period and will report urine output measured in milliliters per kilogram per hour. | 24 hours | |
Secondary | Mean arterial blood pressure during hospitalization | Following surgery, patients will be hospitalized for 24 hours. During this time, the investigators will monitor Mean arterial pressure | 24 hours | |
Secondary | The intraoperative intravenous fluid balance | Throughout the surgical procedure, the investigators will meticulously monitor and record the precise amount of fluid administered in milliliters. | the duration of the surgery |
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