Light Sensitivity Clinical Trial
Official title:
Characterization of Eye Movement Behaviour and Pupil Size Through Eye-tracking in Natural Outdoor and Indoor Scenes
In this study, the researchers will be using eye tracking and detailed lighting measurements to understand how different types of indoor and outdoor lighting affect the eye movements and pupil sizes of our participants. Participants will be paired up and undergo six eye tracking sessions, split across two appointments. Each appointment will involve viewing either indoor or outdoor scenes, and before each session, participants will spend time adapting to the lighting conditions. Overall, each participant will spend 24 minutes being tracked, and the entire study will take about 2-3 hours to complete. The investigators expect differences in eye movements and pupil size between indoor and outdoor scenes.
Status | Recruiting |
Enrollment | 24 |
Est. completion date | July 31, 2024 |
Est. primary completion date | August 31, 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility | Inclusion Criteria: - No previous eye-surgeries or ocular impairments like anisometropia, amblyopia, strabism, cataract, watery eyes or hanging eye lids - Normal or corrected-to-normal visual acuity (+3dpt. to -5dpt.) - Normal colour vision - Normal binocular vision Exclusion Criteria: - Any use of medications or drugs that influence photosensitivity or the ability to concentrate - Excessive alcohol and/or drug use - Presence of psychiatric disorders - Poor sleep quality - Diagnosed with epilepsy |
Country | Name | City | State |
---|---|---|---|
Germany | Max Planck Institute for Biological Cybernetics | Tübingen |
Lead Sponsor | Collaborator |
---|---|
Technical University of Munich | Max-Planck Institute for Biological Cybernetics |
Germany,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Saccade frequency - Indoor scene 1 | Number per second [n/s] | Baseline | |
Primary | Saccade frequency - Indoor scene 2 | Number per second [n/s] | Baseline | |
Primary | Saccade frequency - Indoor scene 3 | Number per second [n/s] | Baseline | |
Primary | Saccade frequency - Outdoor scene 1 | Number per second [n/s] | Baseline | |
Primary | Saccade frequency - Outdoor scene 2 | Number per second [n/s] | Baseline | |
Primary | Saccade frequency - Outdoor scene 3 | Number per second [n/s] | Baseline | |
Primary | Saccade amplitude - Indoor scene 1 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade amplitude - Indoor scene 2 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade amplitude - Indoor scene 3 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade amplitude - Outdoor scene 1 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade amplitude - Outdoor scene 2 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade amplitude - Outdoor scene 3 | Mean angular distance traveled [°] | Baseline | |
Primary | Saccade velocity - Indoor scene 1 | Mean peak velocity [°/s] | Baseline | |
Primary | Saccade velocity - Indoor scene 2 | Mean peak velocity [°/s] | Baseline | |
Primary | Saccade velocity - Indoor scene 3 | Mean peak velocity [°/s] | Baseline | |
Primary | Saccade velocity - Outdoor scene 1 | Mean peak velocity [°/s] | Baseline | |
Primary | Saccade velocity - Outdoor scene 2 | Mean peak velocity [°/s] | Baseline | |
Primary | Saccade velocity - Outdoor scene 3 | Mean peak velocity [°/s] | Baseline | |
Primary | Fixation duration - Indoor scene 1 | Mean fixation duration [s] | Baseline | |
Primary | Fixation duration - Indoor scene 2 | Mean fixation duration [s] | Baseline | |
Primary | Fixation duration - Indoor scene 3 | Mean fixation duration [s] | Baseline | |
Primary | Fixation duration - Outdoor scene 1 | Mean fixation duration [s] | Baseline | |
Primary | Fixation duration - Outdoor scene 2 | Mean fixation duration [s] | Baseline | |
Primary | Fixation duration - Outdoor scene 3 | Mean fixation duration [s] | Baseline | |
Primary | Fixation frequency - Indoor scene 1 | Number per minute [n/min] | Baseline | |
Primary | Fixation frequency - Indoor scene 2 | Number per minute [n/min] | Baseline | |
Primary | Fixation frequency - Indoor scene 3 | Number per minute [n/min] | Baseline | |
Primary | Fixation frequency - Outdoor scene 1 | Number per minute [n/min] | Baseline | |
Primary | Fixation frequency - Outdoor scene 2 | Number per minute [n/min] | Baseline | |
Primary | Fixation frequency - Outdoor scene 3 | Number per minute [n/min] | Baseline | |
Primary | Pupil size - Indoor scene 1 | Mean pupil size [mm] | Baseline | |
Primary | Pupil size - Indoor scene 2 | Mean pupil size [mm] | Baseline | |
Primary | Pupil size - Indoor scene 3 | Mean pupil size [mm] | Baseline | |
Primary | Pupil size - Outdoor scene 1 | Mean pupil size [mm] | Baseline | |
Primary | Pupil size - Outdoor scene 2 | Mean pupil size [mm] | Baseline | |
Primary | Pupil size - Outdoor scene 3 | Mean pupil size [mm] | Baseline | |
Primary | Melanopic irradiance - Indoor scene 1 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Melanopic irradiance - Indoor scene 2 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Melanopic irradiance - Indoor scene 3 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Melanopic irradiance - Outdoor scene 1 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Melanopic irradiance - Outdoor scene 2 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Melanopic irradiance - Outdoor scene 3 | Irradiance [W/(sqm*nm)] | Baseline | |
Primary | Photopic illuminance - Indoor scene 1 | Illuminance [lux] | Baseline | |
Primary | Photopic illuminance - Indoor scene 2 | Illuminance [lux] | Baseline | |
Primary | Photopic illuminance - Indoor scene 3 | Illuminance [lux] | Baseline | |
Primary | Photopic illuminance - Outdoor scene 1 | Illuminance [lux] | Baseline | |
Primary | Photopic illuminance - Outdoor scene 2 | Illuminance [lux] | Baseline | |
Primary | Photopic illuminance - Outdoor scene 3 | Illuminance [lux] | Baseline | |
Secondary | Subjective scene ratings - Indoor scene 1 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Subjective scene ratings - Indoor scene 2 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Subjective scene ratings - Indoor scene 3 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Subjective scene ratings - Outdoor scene 1 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Subjective scene ratings - Outdoor scene 2 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Subjective scene ratings - Outdoor scene 3 | Unabbreviated scale titles (1)., min. and max, values (2.), score assessment (3.):
1. "How beautiful is this scene to you?" 2. "1 = not beautiful at all; 10 = extremely beautiful" 3. No better or worse outcome 1. "How would you rate the brightness of this scene?" 2. "1 = dimly lit room; 10 = bright sunny day" 3. No better or worse outcome 1. "How visually comfortable did you find this scene?" 2. "1 = No discomfort; 10 = Very uncomfortable" 3. No better or worse outcome 1. "How would you rate the complexity of the scene (e.g. colour contrasts, different object identities, moving objects)?" 2. "1 = very simple; 10 = Very complex" 3. No better or worse outcome 1. "How sleepy do you currently feel" 2. "1 = Extremely alert; 10 = Extremely sleep, can't keep awake" 3. Lower score is better |
Baseline | |
Secondary | Geographical scene location - Indoor scene 1 | Longitude and latitude [°] | Baseline | |
Secondary | Geographical scene location - Indoor scene 2 | Longitude and latitude [°] | Baseline | |
Secondary | Geographical scene location - Indoor scene 3 | Longitude and latitude [°] | Baseline | |
Secondary | Geographical scene location - Outdoor scene 1 | Longitude and latitude [°] | Baseline | |
Secondary | Geographical scene location - Outdoor scene 2 | Longitude and latitude [°] | Baseline | |
Secondary | Geographical scene location - Outdoor scene 3 | Longitude and latitude [°] | Baseline | |
Secondary | Ambient temperature - Indoor scene 1 | Temperature [°C] | Baseline | |
Secondary | Ambient temperature - Indoor scene 2 | Temperature [°C] | Baseline | |
Secondary | Ambient temperature - Indoor scene 3 | Temperature [°C] | Baseline | |
Secondary | Ambient temperature - Outdoor scene 1 | Temperature [°C] | Baseline | |
Secondary | Ambient temperature - Outdoor scene 2 | Temperature [°C] | Baseline | |
Secondary | Ambient temperature - Outdoor scene 3 | Temperature [°C] | Baseline |
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
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