Leukemia Clinical Trial
Official title:
Laboratory Studies Into the Pathology of Leukaemia
Ongoing laboratory work into the pathology of Leukaemia:
The investigators will test AML samples sent to the diagnostic laboratory from participants
with newly diagnosed or relapsed/refractory AML. Samples will be sent from district general
hospitals and teaching hospitals.
Results will be returned to referring clinicians in the same way investigators currently
return results for samples sent for standard tests. The service will be advertised through
the Royal Marsden Website with visibility to both participants and HCPs). The investigators
will also inform all the clinicians involved in the AML working party (Dr Taussig is a member
of the AML working group).
In addition we are looking at diagnostic approaches to IDH 1 and 2 mutation identification.
An initial comparison of 50 samples by three analysis methods will be conducted.
IDH1 and IDH2 variant discovery will first be performed using an established standard in
house SOP (SOP: SMD103) for CE-SSCA
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