Leukemia Clinical Trial
Official title:
Determining the Clinicopathological Significance of CaMKIIgamma Activation in AML
Verified date | March 2015 |
Source | Southwest Oncology Group |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
RATIONALE: Studying samples of blood and bone marrow from patients with cancer in the
laboratory may help doctors learn more about changes that occur in DNA and identify
biomarkers related to cancer.
PURPOSE: This research study is looking at blood and bone marrow samples from patients with
previously untreated primary acute myeloid leukemia.
Status | Completed |
Enrollment | 132 |
Est. completion date | June 2009 |
Est. primary completion date | June 2009 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 56 Years and older |
Eligibility |
DISEASE CHARACTERISTICS: - Cryopreserved specimens of marrow or peripheral blood from patients enrolled in clinical trial SWOG-9333 and meeting the following criteria: - Diagnosis of primary acute myeloid leukemia - No M3 disease - Previously untreated disease - Randomized to remission induction chemotherapy with mitoxantrone hydrochloride and etoposide (Arm II) PATIENT CHARACTERISTICS: - Not specified PRIOR CONCURRENT THERAPY: - See Disease Characteristics |
Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Southwest Oncology Group | National Cancer Institute (NCI) |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Association of specific clinicopathological variables and outcomes with calmodulin-dependent protein kinase II-? (CaMKII?) activation (autophosphorylation) | upon receipt of specimens | No |
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