Leukemia Clinical Trial
Official title:
Intensive Induction for Newly Diagnosed Acute Myelogenous Leukemia
Verified date | February 2011 |
Source | The Cleveland Clinic |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
RATIONALE: Drugs used in chemotherapy, such as mitoxantrone, cytarabine, and etoposide, work
in different ways to stop the growth of cancer cells, either by killing the cells or by
stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill
more cancer cells.
PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating
patients with newly diagnosed acute myeloid leukemia.
Status | Completed |
Enrollment | 40 |
Est. completion date | May 2008 |
Est. primary completion date | April 2007 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 16 Years and older |
Eligibility |
DISEASE CHARACTERISTICS: - Diagnosis of acute myeloid leukemia - Previously untreated disease - Previous hydroxyurea and/or corticosteroids are acceptable - No preexisting history of a hematologic disorder - Myelodysplastic features allowed - No acute leukemia secondary to previous therapy - No leukemic meningitis PATIENT CHARACTERISTICS: - Bilirubin < 2.0 mg/dL (unless felt to be increased because of hepatic infiltration with leukemia) - Creatinine < 2.0 mg/dL - Pregnant or lactating patients are ineligible - Fertile patients must use effective contraception - No history of or active congestive heart failure PRIOR CONCURRENT THERAPY: - See Disease Characteristics |
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
The Cleveland Clinic | National Cancer Institute (NCI) |
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