Lymphoma Clinical Trial
Official title:
Evaluation of Loratadine for Granulocyte-Colony Stimulating Factor Induced Bone Pain in Patients With Hematologic Malignancies
The purpose of this project is to assess the efficacy of loratadine in decreasing the incidence and severity of bone pain following G-CSF administration in patients with hematologic malignancies, patients undergoing mobilization of hematopoietic progenitor cells, and patients who have undergone an autologous hematopoietic cell transplant. This is a different patient population than those being assessed in current clinical trials.
Objectives
The primary objective is to determine the incidence of bone pain following G-CSF
administration in patients with hematologic malignancies, patients undergoing mobilization of
hematopoietic progenitor cells, and patients who have undergone an autologous hematopoietic
cell transplant. Incidence will be determined via patient-reported incidence following G-CSF
administration.
Secondary objectives include determining the efficacy of loratadine for bone pain prevention
as indicated by a decrease in incidence and a decrease in severity (questions 4 and 5 of the
survey).
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