Length of Hospital Stay Clinical Trial
Official title:
Normal Saline Versus Hypertonic Saline in the Treatment of Bronchiolitis
Verified date | June 2017 |
Source | Makassed General Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Background: Bronchiolitis is one of the most common and costly respiratory diseases in
infants and young children. Despite the high prevalence and morbidity of bronchiolitis,
therapy remains controversial. Supportive care ensuring adequate hydration and oxygenation
remains the cornerstone of therapy for these infants.
Over the past 2 decades, research on bronchiolitis management has explored the use of
nebulized hypertonic saline that rehydrate the airway surface liquid and improve mucociliary
clearance, as well as reduce airway edema.
Aim:The aim of this study is to investigate whether the addition of frequently nebulized
hypertonic saline to standard therapy affects the length of stay (LOS) of moderately ill
infants hospitalized with bronchiolitis.
Status | Completed |
Enrollment | 128 |
Est. completion date | May 31, 2017 |
Est. primary completion date | May 30, 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A to 2 Years |
Eligibility |
Inclusion Criteria: - Infants up to 24 months of age with diagnosis of acute bronchiolitis - In accordance with 2006 American Academy of Pediatrics (AAP) definition of bronchiolitis,we did not limit to the first episode of wheeze - Patients with the diagnosis of bronchiolitis Exclusion Criteria: - Chronic lung or heart disease (hemodynamically significant cardiac disease, chronic lung disease / bronchopulmonary dysplasia requiring diuretics or oxygen) - Cystic fibrosis, trisomy 21, immunodeficiency / transplant recipient, neuromuscular disease |
Country | Name | City | State |
---|---|---|---|
Lebanon | Makassed General Hospital | Beirut |
Lead Sponsor | Collaborator |
---|---|
Makassed General Hospital |
Lebanon,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Length of stay | from date of admission to discharge date | an average of 5 days | |
Secondary | transfer to pediatric intensive care unit (PICU) | admission to PICU | an average of 3 days | |
Secondary | use of mechanical ventilator | clinical worsening of patients requiring mechanical ventilator | an average of 3 days |
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