Leiomyoma Clinical Trial
Official title:
Phase 1 Study of Misoprostol in Reducing Intraoperative Bleeding in Myomectomy Operations
The aim of this research work is to assess the effect of using single preoperative dose of rectal misoprostol in abdominal myomectomy operations on blood loss, duration of the operation and possible operative complications
This study is a randomized, double-blind, controlled study that will be conducted in Ain
Shams University Maternity Hospital.
A total of 50 women scheduled to undergo myomectomy for symptomatic uterine myoma will be
included in this study after taking their consent for this clinical trial after full
explanation of the trial.
The total of 50 included patients will be divided into two groups: Group A (Study group;):
will Include 25 patients undergoing myomectomy operation will receive two tablets of
misoprostol (400 mcg) rectally two hours before the operation.Group B (Control group): will
Include 25 patients undergoing myomectomy operation will not receive misoprostol before the
operation.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04172272 -
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
|
N/A | |
| Terminated |
NCT02940041 -
Concordance Between Sonography Amd MRI for Presurgical Diagnosis of Uterine Mesenchymal Malignant Tumors
|
||
| Withdrawn |
NCT00768742 -
Safety and Effectiveness Study of RF Ablation of Uterine Fibroids to Reduce Menstrual Bleeding: the Fibroid Ablation Study
|
N/A | |
| Completed |
NCT00156195 -
Study to Evaluate the Safety of Asoprisnil in the Treatment of Uterine Fibroids
|
Phase 3 | |
| Completed |
NCT00152256 -
A Study to Evaluate of the Safety and Effectiveness of Asoprisnil in Treating Women With Uterine Fibroids
|
Phase 3 | |
| Completed |
NCT00160381 -
A Study to Evaluate the Safety and Effectiveness of Asoprisnil in the Treatment of Uterine Fibroids
|
Phase 3 | |
| Recruiting |
NCT04214457 -
Development of a Predictive Model for Early Differential Diagnosis of Uterine Leiomyomas and Leiomyosarcomas
|
||
| Completed |
NCT00044876 -
Treatment of Uterine Fibroids With CDB-2914, an Experimental Selective Progesterone Receptor Antagonist
|
Phase 2 | |
| Completed |
NCT02889848 -
Safety and Tolerability of Collagenase Clostridium Histolyticum (EN3835) to Treat Uterine Leiomyoma (Fibroids)
|
Phase 1 | |
| Recruiting |
NCT04145518 -
Mechanistic Characterization of Uterine Pain
|
Phase 4 | |
| Completed |
NCT01816815 -
Study in Healthy Tubal Ligated Women to Evaluate Pharmacodynamics, Safety and Pharmacokinetics of BAY1002670
|
Phase 1 | |
| Completed |
NCT00891657 -
Post Market Study for an Adhesion Barrier Following Laparoscopic Myomectomy
|
N/A | |
| Completed |
NCT00156156 -
Study of Asoprisnil in the Treatment of Uterine Fibroids.
|
Phase 3 | |
| Recruiting |
NCT05538689 -
Surgical Myomectomy Followed by Oral Myfembree Versus Standard of Care Trial (SOUL)
|
Phase 4 | |
| Active, not recruiting |
NCT03323905 -
Single Arm Study Using the Symphony -- MRI Guided Focused Ultrasound System for the Treatment of Leiomyomas
|
N/A | |
| Terminated |
NCT03342859 -
Mode of Action Study of Vilaprisan and Ulipristal Acetate in Patients With Uterine Fibroids for Whom Surgery is Planned
|
Phase 1 | |
| Recruiting |
NCT06135870 -
Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)
|
||
| Completed |
NCT02777203 -
Power Morcellation Systems for Laparoscopic Hysterectomy and Myomectomy
|
N/A | |
| Completed |
NCT02189083 -
Study of Tumor-shrinking Decoction (TSD) to Treat Symptomatic Uterine Fibroids
|
Phase 3 | |
| Completed |
NCT01123603 -
Lower Urinary Tract Infection (UTI) Evaluation in Women With Uterine Leiomyomata
|
N/A |