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NCT05650008 Clinical Trial

Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

Left Ventricular Dysfunction Clinical Trial

Official title:
Effects of Intrathecal Local Anesthetics on Left Ventricular Global Longitudinal Strain

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05650008
Other study ID # 21263
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 1, 2023
Est. completion date October 10, 2023

Study information
Verified date November 2023
Source Milton S. Hershey Medical Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The objective of this study is to assess the effects of intrathecal local anesthetics on left ventricular global longitudinal strain (LVGLS) using transthoracic echocardiography (TTE).

Recruitment information / eligibility
Status Completed
Enrollment 10
Est. completion date October 10, 2023
Est. primary completion date October 10, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Adult patients undergoing elective knee and hip replacements under spinal anesthesia Exclusion Criteria: - Patients who do not wish to consent - Patients with contraindications to TTE - Patients with reduced left ventricular systolic function as defined by LV ejection fraction < 50% on pre-operative echocardiography - Patients with body mass index greater than 40 - Non-English-speaking subjects - Cognitively impaired adults

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Intrathecal local anesthesia
Administration of local anesthetic into intrathecal space to achieve surgical anesthesia

Locations
Country Name City State
United States Milton S. Hershey Medical Center Hershey Pennsylvania

Sponsors (1)
Lead Sponsor Collaborator
Milton S. Hershey Medical Center

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Left Ventricular Global Longitudinal Strain 5 minutes
Secondary Left Ventricular Ejection Fraction 5 minutes
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