Does Lead Burden Alter Neuropsychological Development?

Status Completed

Clinical Trial Summary

Inner city children are at an increased risk for lead overburden. This in turn affects cognitive functioning. However, the underlying neuropsychological effects of lead overburden and its age-specific effects have not been well delineated. This study is part of a larger study on the effects of lead overburden on the development of attention and memory. The larger study is using a multi-model approach to study the effects of lead overburden on these effects including the event-related potential (ERP), electrophysiologic measures of attention and memory are studied. Every eight months, for a total of three sessions the subjects will complete ERP measures of attention and memory which require them to watch various computer images while wearing scalp electrodes recording from 11 sites. It is this test that we are going to be doing on CRC. There will be 30 lead overburdened children recruited from the larger study for participation in the ERP studies on CRC. These 30 children will be matched with 30 children without lead overburden. This portion of the study is important in providing an index of physiological functioning to be used along with behaviorally based measures of attention and memory, and for providing information about the different measures.

Clinical Trial Description

n/a

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Lead Poisoning

Clinical Trial Details

NCT number	NCT00000104
Study type	Observational
Source	National Center for Research Resources (NCRR)
Contact
Status	Completed
Phase	N/A

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01573013` - Iron Fortification Trail Using NaFeEDTA in Iron Deficient Lead-exposed Children	N/A
Withdrawn	`NCT00552630` - Penicillamine Chelation for Children With Lead Poisoning	Phase 2/Phase 3
Completed	`NCT00014885` - Bone Lead Levels and College Achievement Scores	N/A
Completed	`NCT00004838` - Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children	N/A
Enrolling by invitation	`NCT05265572` - Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump	N/A
Completed	`NCT01739166` - QI Study of a Practice Facilitator's Impact in Working With Clinics on Improving Dental, Lead & Obesity Measures for Children	N/A
Completed	`NCT00285610` - Early Exposure to Lead and Adult Antisocial Outcomes	N/A
Completed	`NCT00011674` - Early Exposure to Lead and Adolescent Development	N/A
Completed	`NCT00374894` - The Combined Effect of 2,3-Dimercaptosuccinic Acid and Multi-Nutrients on Children in Lead Poisoning	N/A
Completed	`NCT00011661` - Social Network Based Intervention to Reduce Lead Exposure Among Native American Children	N/A
Recruiting	`NCT03256383` - Plan for Testing Fingerstick Bloods on Magellan Systems	N/A
Recruiting	`NCT05950386` - Effects of Lead Exposure on Ferroptosis Pathway
Completed	`NCT02346188` - Effects of Iron and/or Zinc Supplementation in Mexican School Children Exposed to Lead	N/A
Completed	`NCT00013858` - Environmental Contaminants and Infant Development	N/A
Completed	`NCT00013819` - Exposure, Dose, Body Burden and Health Effects of Lead	N/A
Active, not recruiting	`NCT05744752` - Effects of Allium Sativum and Moringa Oleifera Extract on Dental Enamel	N/A
Completed	`NCT00012480` - Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm	N/A
Completed	`NCT00011726` - Lead Mobilization & Bone Turnover in Pregnancy/Lactation	N/A
Completed	`NCT00023101` - Lead, Endocrine Disruption and Reproductive Outcomes	N/A
Terminated	`NCT04498845` - RECLEAN Pilot Study	N/A