Laryngopharyngeal Reflux Clinical Trial
Acid reflux can cause many symptoms in the throat, including discomfort or pain, and
difficulty with breathing and voice problems. Doctors have different ways of diagnosing and
treating the reflux that causes these symptoms, and they are trying to better understand
what the best ways are to treat the patients with these symptoms.
Usually, a doctor will prescribe medication for reflux based on the symptoms a patient
complains of. Sometimes it works and the patient gets better, sometimes it does not work and
the patient's condition does not improve. The doctor will also use findings from an
examination with an endoscope in the patient's throat to see if there is any damage that
might have been caused by reflux. One new device that doctors use to help them diagnose
reflux has a sensor on the end of a tube that goes through the nose and rests in the throat.
This sensor measures the acid reflux for 24 hours, showing the doctor when acid reflux
occurs.
The study doctors are performing this research study to help them understand more about acid
reflux disease, and the best ways to diagnose and treat their patients who have acid reflux.
The study involves procedures, medications and devices that are already used regularly in
doctors' offices and hospitals. The experimental part of this research is blinding the study
doctor to the results of the pH study until the end of a three month course of antireflux
medication, and performing a second pH study to measure change in acid exposure.
Hypothesis: The Restech pH study helps identify patients who will respond positively to acid
inhibitory therapy, and patients whose study normalizes will have better Symptomatic
response rates than those whose pH levels fail to normalize.
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Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
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| Completed |
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|
Phase 3 | |
| Recruiting |
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|
N/A | |
| Not yet recruiting |
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N/A | |
| Withdrawn |
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|
Phase 4 | |
| Completed |
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|
N/A | |
| Completed |
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|
N/A | |
| Terminated |
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| Completed |
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|
N/A | |
| Completed |
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|
N/A | |
| Not yet recruiting |
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|
Phase 4 | |
| Not yet recruiting |
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|
Phase 3 | |
| Recruiting |
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| Withdrawn |
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|
N/A | |
| Completed |
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|
Phase 1 | |
| Completed |
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| Recruiting |
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Phase 4 | |
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||
| Terminated |
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|
Phase 4 |