Laparotomy Clinical Trial
Official title:
Professor and Head of Department of Surgery Dow University Hospital DUHS
Brief study Introduction/background Laparostomy is defined is a surgical procedure in which
abdominal cavity is opened and left opened deliberately because of difficult primary closure
or when primary closure is avoided due to severe intraabdominal sepsis, trauma and risk of
abdominal compartment syndrome.
Patients and methods Retrospective Proforma based study conducted from 1st May 2014-31st May
2018. All patients admitted through emergency diagnosed clinically with peritonitis,
intraabdominal sepsis and abdominal trauma managed with laparotomy and laparostomy were
included in the study. On laparotomy primary cause was identified and controlled with damaged
control surgery to save the lives and abdomen was left open with temporary abdominal wall
cover of urine bag stitched all around either with skin or external oblique aponeurosis
temporarily for second relook laparotomy after 24-48 hours. On second relook of abdomen
haemostasis secured and abdomen was washed with normal saline, any missed pathology
identified and controlled and abdomen was closed in some patient when there was no need to
recheck the abdomen while in other patients abdominal content were covered again temporarily
with urine bag. All patients were managed by the team of surgery and ICU. Finally abdomen was
closed by deep tension suture DTS or direct layered closure of abdominal wall.
Detail study Introduction Laparostomy is a surgical procedure in which abdominal cavity is
opened and left opened deliberately called open abdomen, an open abdomen is based on the
principle of incision and drainage of an abscess and leaving the wound open for free
drainage, washouts and multiple dressings1.
Usually abdomen is closed primarily in all abdominal surgeries but some time it is difficult
to close the abdomen primarily to avoid intraabdominal hypertension because the risk of
abdominal compartment syndrome and to manage severe intraabdominal sepsis2. Trauma required
damage control surgery 3, and other complex abdominal pathologies, injuries due to explosive
devices4, laparostomy and finally staged abdominal closure or DTS deep tension sutures are
used to close the abdomen5. Multiple techniques are used to close the abdomen temporarily
after laparotomy to have a second relook laparotomy6. Laparostomy is a complex procedure and
it is difficult to identify which is the best technique for temporary abdominal closure,
primary fascial closure, mesh, plastic sheet, bagota bag, urine bag, vacuum assisted closure
are commonly used methods to cover the abdominal content to prevent the risk of injury
evisceration and direct exposure to the atmosphere7.
Our objective is to identify the indications and outcome of laparostomy in emergency
laparotomy and prevent the abdominal compartment syndrome, in critically ill patients due to
fecal peritonitis, intraabdominal sepsis and trauma.
Patients and methods Retrospective Proforma based study conducted from 1st May 2014-31st May
2018 at Dow International Hospital Ojha Campus Dow University of Health Sciences Karachi
Pakistan.
Inclusion Criteria: all critically ill patients admitted through emergency, diagnosed with
peritonitis, intraabdominal sepsis and trauma managed with damaged control surgery initially
along with laparostomy in which the abdomen was left open with temporary abdominal cover to
have a relook laparotomy were included in the study Exclusion Criteria: Patients diagnosed
clinically with peritonitis and trauma but managed by primary abdominal wall closure were
excluded from the study.
Initially all Patients were optimized and resuscitated and all necessary investigations were
send in emergency eg blood grouping and cross matching, blood complete picture, serum
electrolyte ,blood urea & creatinine screening for hepatitis. Antibiotic cover, fluid and
electrolyte support was given to all patients. FFP arranged according to the requirement.
Imaging performed where necessary in stable patients.
On laparotomy primary cause was identified and managed with damaged control surgery along
with abdominal washout and abdomen was covered with a urine bag open from the center to make
a sheet then sutured all around with the skin or external oblique aponeurosis. All patients
were managed in the ICU initially for a second relook laparotomy.
Second relook laparotomy was performed after 24-48 hours abdomen was washed with normal
saline haemostasis secured and any missed primary pathology was identified and controlled.
Abdomen was closed in few patient where no need to recheck the abdomen, while in remaining
patients abdominal content were covered again with urine bag who require multiple washouts
and dressing. All patients managed by the team of ICU, anesthesia, surgeon, and physician
from critical care medicine. Morbidity and mortality happen recorded during the period of
hospital stay Patient discharged after complete recovery with the final closure of abdominal
wall either with deep tension suture DTS figure 4 or direct layered closure of abdominal
wall. Data was collected and recorded on a pre designed research Proforma made for this
study. SPSS version 20 was used to analyze the data.
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