QL Block With Exparel in Colectomy

Status Completed

Clinical Trial Summary

The purpose of this study is to determine if using a different type of injection of local anesthestic (pain medicine) in between the muscle layers of the abdominal wall (called a quadratus lumborum block) will improve pain control and be easier to manage after surgery than the current standard of care epidural (spinal injection) pain relief for patients undergoing laparoscopy colectomy.

Clinical Trial Description

Participants in this study will receive exparel via an abdominal muscle nerve block procedure immediately prior to their operation. Participants will be in this study for 96 hours following surgery, which is typically 3 days. During participation, the study staff will review participant's electronic health records for pain scores and pain medication needs. Participants that receive the quadratus lumborum block, may experience improved pain control and/or reduced side effects compared to the epidural pain relief option, but it is not known yet whether this will be the case. The most common risk is being sore in the flank where the block was placed. Other risks of the block rarely occur (less than .5-1%), these can include infection, allergy to the local anesthetic, bleeding, damage to the nerve, seizures, abnormal heart rhythms, and cardiac arrest. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03827291
Study type	Interventional
Source	Duke University
Contact
Status	Completed
Phase	Phase 4
Start date	October 31, 2019
Completion date	December 9, 2022

View Details

See also
Status	Clinical Trial	Phase
Enrolling by invitation	`NCT03234543` - Remote Ischemic Conditioning in Abdominal Surgery	N/A
Recruiting	`NCT01719796` - Effect of TAP Block on Ventilatory Function Following Abdominal Surgery	Phase 2
Completed	`NCT02596269` - Nefopam/Fentanyl Postoperative Intravenous Patient-Controlled-Analgesia	Phase 2/Phase 3
Completed	`NCT00364741` - Supplemental Oxygen and Complications After Abdominal Surgery (The PROXI-trial)	Phase 4
Completed	`NCT01723280` - Supplemental Oxygen - Effect on Occurrence of Subsequent Cancer After Abdominal Surgery (Follow-up of the PROXI Trial)	N/A
Terminated	`NCT00514566` - PDS vs Polyamide for Midline Abdominal Closure	N/A
Recruiting	`NCT06089551` - Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery	Phase 4
Withdrawn	`NCT03966768` - DuraMesh Laparotomy Study	N/A
Recruiting	`NCT04985695` - Influence of Analgesic Technique on Post Operative Rehabilitation After Median Laparotomy	N/A
Recruiting	`NCT03739944` - Different Surgical Approaches in Patients of Early-stage Cervical Cancer	Phase 3
Terminated	`NCT01890408` - Continuous Preperitoneal Infusion of Ropivacaine After Open Liver Resection: Effect on Post-operative Recovery and Morbidity.	Phase 2
Recruiting	`NCT00544583` - Continuous Versus Interrupted Abdominal Wall Closure After Emergency Midline Laparotomy	Phase 2/Phase 3
Recruiting	`NCT04256798` - Perioperative Respiratory Care and Outcomes for Patients Undergoing High Risk Abdominal Surgery	Phase 3
Recruiting	`NCT03738969` - Longitudinal Study of Different Surgical Approaches in Chinese Patients of Uterine Cervical Cancer
Completed	`NCT03989570` - Transversus Abdominis Plane Block Versus Erector Spinae Plane Block	N/A
Not yet recruiting	`NCT04266535` - TCI vs Manually Controlled Infusion of Propofol
Completed	`NCT04065607` - Indications and Outcome of Laparostomy
Completed	`NCT01040013` - Gut Oxygenation and Laparoscopy	Phase 2
Completed	`NCT00637936` - Respiratory Effects of Perioperative Oxygen During General Anaesthesia	Phase 4
Recruiting	`NCT03963882` - NAC Followed by RH for the Treatment of LACC	Phase 2