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Effects of Comprehensive Intestinal Protection Strategy on Postoperative Intestinal Complications — CIPS  

Laparotomy Clinical Trial

Official title:
Effects of Comprehensive Intestinal Protection Strategy on Postoperative Intestinal Complications in Patients Undergoing Laparotomy With General Anesthesia

Clinical Trial Summary

To investigate the morbidity of intestinal injury after open surgery and observe the effect of comprehensive intestinal protection strategy on postoperative intestinal complications in patients undergoing laparotomy with general anesthesia.

Clinical Trial Description

Perioperative intestinal injury is one of the common tissues and organs injury in surgical practice. However, there is a lack of effective means of prevention and treatment.The investigators previously found that ischemic preconditioning, IPC, and dexmedetomidine has protective effects on intestinal mucosal injury.

However, the combined effect of various factors has not been clinically validated. To explore the effect of comprehensive intestinal protection strategy on postoperative intestinal complications in patients undergoing laparotomy with general anesthesia,the investigators select the patients undergoing open surgery under general anesthesia as the study subjects and the concentration of intestinal fatty acid binding protein (I-FABP) as well as the incidence of digestive system complications in one week after operation are the main observation indexes. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03216759
Study type Interventional
Source Nanfang Hospital of Southern Medical University
Contact Cai Li, M.D
Phone +86-18602017796
Email licaisysu@163.com
Status Not yet recruiting
Phase N/A
Start date August 2017
Completion date December 2018
View Details
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