Evaluation of Laparoscopic Non Anatomical Liver Resection in Hepatic Pathology

Laparoscopic Liver Resection Clinical Trial

Official title:

Evaluation of Laparoscopic Non Anatomical Liver Resection in Hepatic Pathology

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06166511
• Other study ID #: Laparoscopic liver resection
• Status: Not yet recruiting
• Phase: N/A
• Start date: January 10, 2024
• Est. completion date: May 10, 2025

Study information

• Verified date: December 2023
• Source: Assiut University
• Contact: N N Adly
• Phone: 01206187141
• Email: nadernasihadly[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Laparoscopy is a type of surgical procedure that allows a surgeon to access the inside of the abdomen and pelvis without making large incisions in the skin.The use of laparoscopy in abdomenal surgeries increases for its great benefits over open surgery as:

1)faster recovery, 2)decrease blood loss, 3)shorter hospital stays, 4)decreased postoperative pain, 5)earlier return to work and resumption of normal daily activity as well as, 6)cosmetic benefits.

few studies discuss the efficacy and safety of using Laparoscopy in liver non anatomical resection.

Description:

this study will include any male and female above 18 that presented with localized liver pathology (as benign hepatic tumours, resectable primary(HCC) or secondary malignancies, hydatid cyst any other hepatic cysts, haemangiomas,etc…...) and underwent laparoscopic non anatomical resection of liver in Assiut university hospitals. Investigators will record the time of operation, number of cases with intra operative mortality or complication and then follow up these patients during time of hospital stay for:

1) post operative pain 2) secondary bleeding and 3) wound infection.

Then follow up these patients in out patient clinic visit for their:

1. satisfaction

2. cosmetic outcomes and

3. rate of recurrence of the pathology.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: May 10, 2025
• Est. primary completion date: March 10, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• any male or female above 18 that has one of the following pathologies and underwent non anatomical hepatic resection:

• hepatic benign tumours as adenoma

• resectable secondary malignancies (2)

• any type of hepatic cysts e.g., hydatid cyst

• HCC on top of liver cirrhosis.

Exclusion Criteria:

• 1) any immunocompromised patient 2) Patient with contraindicdtions to use laparoscopy. 3) patient who are difficult to follow up.

Related Conditions & MeSH terms

• Laparoscopic Liver Resection

Intervention

Procedure:
• Laparoscopic liver resection
Using Laparoscopy in liver resection

Locations

Country	Name	City	State
Egypt	Assuit University hospitals	Assiut	Assuit

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Country where clinical trial is conducted

Egypt, 

References & Publications (1)

Garlipp B, Gibbs P, Van Hazel GA, Jeyarajah R, Martin RCG, Bruns CJ, Lang H, Manas DM, Ettorre GM, Pardo F, Donckier V, Benckert C, van Gulik TM, Goere D, Schoen M, Pratschke J, Bechstein WO, de la Cuesta AM, Adeyemi S, Ricke J, Seidensticker M. Secondary technical resectability of colorectal cancer liver metastases after chemotherapy with or without selective internal radiotherapy in the randomized SIRFLOX trial. Br J Surg. 2019 Dec;106(13):1837-1846. doi: 10.1002/bjs.11283. Epub 2019 Aug 19. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of intra operative mortality	Number of cases die intra operative	2 years
Primary	Length of operation	Time of operation	2 years
Primary	Post operative pain	Pain scale post operative	2 years
Primary	Incidence of intra operative complications	Type of complications and Its incidence	2 years
Primary	Length of hospital stay	Time spended by cases in hospital	2 years
Primary	Incidence of post operative complications	Type and incidence of post operative complications	2 years
Secondary	Cosmetic outcome	Patient cosmetic sutisfacton	2 years
Secondary	Incidence of recurrence of pathology	Number of cases with same pathology recurrence	2 years