Central China Rosai-Dorfman Disease Registry — CCR-DDR  

Langerhans Cell Histiocytosis Clinical Trial

Official title: A Trial to Evaluate the Long Term Prognosis in Rosai-Dorfman Disease

Status Recruiting

Clinical Trial Summary

This is a research study among patients with Rosai-Dorfman disease.

Clinical Trial Description

Rosai-Dorfman disease is a rare disorder characterized by overproduction (proliferation) and accumulation of a specific type of white blood cell (histiocyte) in the lymph nodes of the body (lymphadenopathy), most often those of the neck (cervical lymphadenopathy). In some cases, abnormal accumulation of histiocytes may occur in other areas of the body besides the lymph nodes (extranodal). These areas include the skin, central nervous system, kidney, and digestive tract. The symptoms and physical findings associated with Rosai-Dorfman disease vary depending upon the specific areas of the body that are affected. The disorder predominantly affects mainly adolescents or young adults. The exact cause of Rosa Dorfman disease is unknown. The purpose of this research study is to learn the prevalence , therapies and long term prognosis of Rosa Dorfman disease. ;

Related Conditions & MeSH terms

• Histiocytosis
• Histiocytosis, Langerhans-Cell
• Langerhans Cell Histiocytosis

• NCT number: NCT05284942
• Study type: Interventional
• Source: Tongji Hospital
• Contact: YIKAI YU, M.D
• Phone: +1-484-995-5917
• Email: yuyikai0509@gmail.com
• Status: Recruiting
• Phase: Phase 4
• Start date: October 1, 2011
• Completion date: June 1, 2022