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Lacrimal Apparatus Diseases clinical trials

View clinical trials related to Lacrimal Apparatus Diseases.

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NCT ID: NCT04952454 Completed - Clinical trials for Functional Epiphora (Tearing Without Any Anatomical Block)

Functional Epiphora Management Via Different Dacryocystorhinostomy (DCR) Techniques

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

135 eyes of 135 patients treated between 2005 and 2017 will be included in this study. The diagnosis of functional epiphora was made based on a patent lacrimal system with a delay in the fluorescein dye disappearance test (FDDT) or dacryoscintigraphy (DSG) without any ocular surface or eyelid abnormalities. The absence of epiphora and normalization of FDDT postoperatively was defined as success. The study's hypothesis is that external DCR with a suitable technique will have better results compared to endonasal and transcanalicular DCR

NCT ID: NCT04637633 Completed - Epiphora Clinical Trials

Topical Cyclosporine-A for Management of Epiphora

CSA-epiphora
Start date: August 15, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

to investigate the clinical outcomes and tolerances of Cyclosporine A (CsA) in treating epiphora in eyes with acquired punctum stenosis

NCT ID: NCT04318652 Completed - Clinical trials for Epiphora Due to Insufficient Drainage

OCT Guided Punctal Stenosis Management

Start date: September 2, 2018
Phase: Phase 4
Study type: Interventional

This is a clinical trial study that was conducted on patients with punctal stenosis.We studied the diameter of stenosed puncta before and after treatment with preserved free steroid eye drops using AS-OCT.

NCT ID: NCT04240938 Completed - Clinical trials for Lacrimal Passage Obstruction

Adult Dacryocystocele Among Patients With Epiphora

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Patients with lacrimal dacryocystocele were chosen for the study. Dacryocystorhinostomy were done for them after their evaluation.

NCT ID: NCT04240431 Completed - Clinical trials for Lacrimal Apparatus Diseases

Level of Lacrimal Passage Obstruction

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

Detect anatomical level of acquired lacrimal passage obstructions among patients with epiphora. They were evaluated and divided into four groups Punctal, Canalicular, Nasolacrimal duct and Mixed groups according to level of obstruction

NCT ID: NCT03731143 Completed - Epiphora Clinical Trials

Management of Lower Punctal Stenosis.

Start date: January 12, 2014
Phase: N/A
Study type: Interventional

a prospective non-randomized study conducted upon 24 patients with severe lower punctual stenosis (grade 0 according to Kashkouli scale) attending at Menoufia University hospitals. The upper punctum and canaliculus were patent. All patients were complaining of epiphora and had a thorough ophthalmological examination including dye disappearance test, and slit-lamp examination. Pigtail probe was used from patent upper punctum to detect the lower stenosed punctum which was opened with a scalpel. Syringing of the lower lacrimal passages was done to confirm its patency and self retaining silicone bicanalicular stent was inserted. The silicone tube was left in place for 6 months before it was removed. Patients were then followed up for 1 year after the surgery.

NCT ID: NCT03706443 Completed - Dry Eye Syndromes Clinical Trials

Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops

Start date: December 5, 2018
Phase: N/A
Study type: Interventional

Cross-over comparison of lipid layer thickness and dry eye symptoms with two artificial tear formulations.

NCT ID: NCT02503956 Completed - Conjunctivitis Clinical Trials

Perforated Punctal Plugs for Treatment of Papillary Conjunctivitis in Otherwise Healthy Patients

Start date: August 2015
Phase: N/A
Study type: Interventional

Assessing efficacy of punctal dilatation with insertion of perforated punctal plugs for the management of acquired punctal stenosis due to allergic conjunctivitis in otherwise healthy patients.

NCT ID: NCT02386774 Completed - Blepharitis Clinical Trials

Innovative Imaging of the Conjunctiva, Cornea, and Ocular Adnexa

INNOV-EYE
Start date: March 21, 2016
Phase: N/A
Study type: Interventional

In vivo confocal microscopy (IVCM) used in tertiary care ophthalmology centers is performed with two reflectance microscopes attached on a mounting with limited movement along the XYZ axes. Consequently, ocular diseases in the central area have been described (mostly cornea and adjacent conjunctiva). Two dermatology IVCM (an handheld small IVCM and a multifluorescent one) present significant innovations that the investigators want to assess in ophthalmology for the diagnosis of conjunctiva, cornea, eyelid and lachrymal tract diseases. The handheld IVCM have unlimited degrees of freedom and a small diameter objective. It could dramatically increase the area accessible to IVCM (whole conjunctiva, eyelids, proximal lachrymal tract) (part 1 of the present study). The fluorescent IVCM allows the use of a wide range of fluorescent markers liable to increase the specificity of the diagnosis by revealing staining patterns corresponding to a specific disease and not to others (part 2 of the study)

NCT ID: NCT01826734 Completed - Clinical trials for Lacrimal Duct Obstruction

Analysis of 86 Dacryoliths at the University Hospital Ostrava

Start date: January 1994
Phase: N/A
Study type: Observational

Background Because dacryoliths occur at low frequency, few studies have focused on their composition. The investigators aimed to present findings from morphological, chemical, and mineralogic analysis of 86 dacryoliths. Methods The team studied 86 dacryoliths obtained during 832 dacryocystorhinostomies (DCR) performed for postsaccal obstruction. The samples were analyzed with atomic infrared spectrometry (80 samples), amino acid analysis (17 samples), scanning electron microscopy, and an electron microprobe with an energy dispersive detector (7 samples).