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VPIA Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration

Labor Pain Clinical Trial

Official title:
Novel Vital-sign Patient-assisted Intravenous Analgesia With Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration: a Prospective Cohort Study

Clinical Trial Summary

This study is a prospective cohort study aiming to evaluate an improved VPIA remifentanil algorithm which would benefit labouring mothers who are unable or unwilling to receive epidural analgesia

Clinical Trial Description

This study trials a new Vital signs-controlled patient-assisted intravenous analgesia (VPIA) regimen using a purpose-built pump that aims to enhance the efficacy, safety and personalization of remifentanil therapy for labouring women. The system studies the parturient's pattern of analgesic use in 15 minute epochs and titrates the demand doses and basal infusion rate to maintain a plasma level of remifentanil that is appropriate for the degree of pain felt.

The system incorporates vital signs (pulse oximetry and heart rate values) into the algorithm which would temporarily stop the pump and step down doses accordingly when predefined critical values are reached. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02733835
Study type Interventional
Source KK Women's and Children's Hospital
Contact Wan Ling Leong, MBBS FANZCA
Phone +6563941081
Email leong.wan.ling@singhealth.com.sg
Status Recruiting
Phase Phase 4
Start date December 2016
Completion date March 2018
View Details
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