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Knee Injury clinical trials

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NCT ID: NCT02649322 Completed - Knee Injury Clinical Trials

Needleless Jet Injected (J-Tip) Lidocaine in Children Undergoing Regional Anesthesia Prior to Knee Arthroscopy

Start date: September 3, 2015
Phase: N/A
Study type: Interventional

Purpose of this study is to investigate the pain outcomes and satisfaction of pain relief for pediatric patients receiving needleless jet-injected (J-Tip) lidocaine prior to regional anesthesia with femoral and/or sciatic nerve block and general anesthesia for arthroscopic knee surgery compared to femoral nerve block and/or sciatic nerve block with needle injected lidocaine prior to regional and general anesthesia.

NCT ID: NCT02637505 Completed - Cartilage Injury Clinical Trials

Norwegian Cartilage Project - Microfracture

Start date: January 2016
Phase: N/A
Study type: Interventional

114 patients between 18 and 50 years with an isolated focal cartilage defect in the knee will be randomized to either receive arthroscopic microfracture or arthroscopic debridement. Both groups will then undergo a systematic physiotherapy training regime for 6-9 months. The groups will then be compared for results, after 3, 6, 12 and 24 months, by using validated patient reported outcome scores (Lysholm, KOOS, Tegner) and EQ5D as well as clinical examination and radiological findings at 2 years (MRI).

NCT ID: NCT02148172 Completed - Clinical trials for Anterior Cruciate Ligament Injury

Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction

Start date: January 2014
Phase: N/A
Study type: Interventional

While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes. Unusually high risks of early-onset osteoarthritis and re-injury, and low rate of return to sport following ACLR all seem to be related to a chronic tendency to land stiff-legged from a jump or hop, which itself may be due to fear of re-injury. Decreased knee bending for force absorption simultaneously decreases performance level and increases risk for injury and arthritic changes. The purpose of the proposed study is to compare a current best-practice plyometric training program to one utilizing body weight support to increase repetition and improve performance in the initial phases. The investigators hypothesize that we will see larger improvements in absorptive capacity of the knee and better confidence in activity immediately following body weight support training, as well as improved retention of training effects after a two-month period.

NCT ID: NCT02065518 Completed - Knee Injury Clinical Trials

Electromyostimulation and Strength Walking for Knee Injuries

KI
Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this project is to compare three treatment regimens for knee injury to the standard rehabilitation protocol: 1) NMES, 2) graduated strength walking (via a weighted vest), and 3) NMES combined with graduated strength walking. Each treatment arm will be supplemented by the standard of care and compared to a group who receive the standard rehabilitation only. The Study will compare the effects of NMES, Strength Walking and combined NMES/ Strength Walking on strength, mobility, symptomatology, and Quality of Life (QOL) in military members with knee injury to a standard rehabilitation protocol program only. All groups will participate in standard rehabilitation protocol. The groups will be assessed over 18 weeks to compare main and interactive effects over time.

NCT ID: NCT02052856 Completed - ACL Injury Clinical Trials

Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Technique

Start date: December 2012
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the incidence and degree of bone tunnel widening between two groups who have undergone anterior cruciate ligament reconstructive surgery. The two groups have undergone different graft fixation methods: an interference screw/suspensory button fixation hybrid technique, and an all-inside suspensory method fixation. Tunnels are created at the time of surgery for graft placement and fixation, but have been known to enlarge post-operatively. Little has been studied on the relatively new all-inside technique. X-rays of the operative knee will be used to assess tunnel width. Secondary outcomes will include clinical evaluation and outcome scoring questionnaires

NCT ID: NCT01971645 Completed - Knee Injury Clinical Trials

Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy

Start date: July 2014
Phase: Phase 3
Study type: Interventional

If preservative-free dexamethasone 0.1 mg/kg (max dose 4 mg) is added to ropivacaine 0.5% 2 mg/kg (max dose 100 mg), then post-PACU opioid consumption will be reduced by 33%.

NCT ID: NCT01950208 Completed - Knee Injury Clinical Trials

The Munich Knee Questionnaire - Development and Validation

MKQ
Start date: August 2012
Phase: N/A
Study type: Observational

the purpose of this study is to develop and validate a new PRO measurement tool for the knee joint, the so-called Munich Knee Questionnaire (MKQ), allowing for a qualitative self-assessment of the Knee Injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC), the Lysholm Knee Score, the Western Ontario Meniscal Evaluation Tool (WOMET) and the Tegner Score.

NCT ID: NCT00894595 Completed - Knee Injury Clinical Trials

Preventing Knee Injuries in Adolescent Female Football Players

Start date: August 2008
Phase: N/A
Study type: Interventional

Football-related knee injuries are common and especially the anterior cruciate ligament (ACL) injury constitute a serious problem in football regardless of the playing level. The purpose of this study is to conduct a randomized controlled trial evaluating the effect of a training program designed to prevent acute knee injury in female adolescent football players. The investigators' hypotheses are: 1. a preventive training program reduces the incidence of ACL injury, and 2. a high match frequency and match play at senior level increase the risk of ACL injury.

NCT ID: NCT00821873 Completed - Knee Injury Clinical Trials

Evaluation of the CR Plug for Repair of Defects Created at the Harvest Site From an Autograft in the Knee.

CRB
Start date: December 2008
Phase: Phase 3
Study type: Interventional

The main objective of this study is to test the ability of an allograft plug to provide a successful repair of an osteochondral defect left at the harvest site during OATS procedure.

NCT ID: NCT00332254 Completed - Knee Injury Clinical Trials

Study to Prevent Cartilage Damage Following Acute Knee Injury.

Start date: March 2006
Phase: Phase 1/Phase 2
Study type: Interventional

Individuals who have had a severe knee injury have an increased risk of developing arthritis of the knee and at a much earlier age than would otherwise be expected. The swelling and inflammation that occur after injury are believed to be responsible for this cartilage damage. The cartilage (material that provides a cushion in the knee) is the primary protection from what is called degenerative arthritis or osteoarthritis. We hope to reduce this swelling and prevent the damage to cartilage that occurs after injury by injecting a medication that blocks one of the proteins responsible for inflammation and cartilage breakdown. This protein is called interleukin-1 and can be inhibited by an interleukin-1 receptor antagonist called anakinra. Anakinra will be injected directly into the injured knee and response to the injection will be measured by symptoms and analysis of cartilage breakdown in the knee fluid and blood.