Knee Injuries Clinical Trial
Official title:
Clinical Outcomes Of Multi-ligament Knee Injuries In Assiut University Hospitals
Multi-ligament knee injuries (MLKI) are devastating injuries. They are defined as injuries to at least two of the four major ligaments in the knee: anterior cruciate ligament, posterior cruciate ligament, lateral collateral ligament (and posterolateral corner) and medial collateral ligament (and posteromedial corner). These injuries are commonly classified using the Schenck classification system. The incidence of these injuries has been reported to be around 0.02-0.20% of all orthopaedic injuries. However, this is likely to be an underestimation due to spontaneous knee reduction and missed injuries. The immediate management of these injuries is crucial in identifying and treating any vascular and nerve injury. The literature has shown poor outcome and residual instability in those who were treated non-operatively. However, the optimal surgical treatment for these injuries is not known, with differences in opinion amongst treating clinicians. There are controversies in the timing of surgery (early versus delayed), single-staged or two-staged procedures and whether the damaged ligaments should be repaired or reconstructed
Approximately 50% of all knee dislocations reduce spontaneously before the physician's arrival. Thus, high suspicion must be held, and literally every MLKI must be treated immediately as a true knee dislocation until proven otherwise. Failing to recognize the whole injury pattern around the knee can lead to disastrous consequences. Thus, an initial interdisciplinary systematic approach obtains top priority. Even though diagnostic image instruments become more and more reliable, physical examination still remains a fundamental element in any accurate assessment of knee dislocation. Several authors describe their own experiences and related treatment strategies of knee dislocation. But although a large number of studies about knee dislocation and MLKI do exist in medical databases, the complexity of this injury, the inhomogeneity of literature, and the persevering controversies in their treatment still make it difficult to draw reliable general conclusions. Although important advances have been made in knee arthroscopy, ligament reconstruction and patient management, recommendations are not always applicable in settings with limited resources available. Challenges encountered in these situations include long delays to presentation, as well as the lack of sufficient access to operating room time, arthroscopic equipment, newer fixation devices, and allografts. Patients are often uninsured; work informally as manual laborers and their access to physiotherapy is very limited. The purpose of this study is to analyse our institution's experience with multi-ligament knee injuries via the following items prevalence, detailed initial management at emergency department, types of these injuries, rationale of definitive treatment, rehabilitation protocol, postoperative complications and functional outcomes. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04554212 -
Blood Flow Restriction Training After Patellar INStability
|
N/A | |
Completed |
NCT04815980 -
Impact of Pilates on Running Mechanics
|
N/A | |
Not yet recruiting |
NCT05484778 -
Analysis of Balance and Functional Hop Tests Used for Return to Sports in Athletes With Lower Extremity Injuries by Dual Task Study
|
N/A | |
Terminated |
NCT02909257 -
Motor-Sparing Femoral Nerve Block Dose
|
Phase 4 | |
Completed |
NCT02540811 -
Clinical Evaluation of dCELL® ACL Scaffold for Reconstruction of the Anterior Cruciate Ligament
|
N/A | |
Recruiting |
NCT03755388 -
Clinical Trial of an MRI Based Patient Specific Focal Knee Resurfacing Implant
|
N/A | |
Recruiting |
NCT00174213 -
Validity and Reliability in Measuring Iliotibial Tract by Using Ultrasound
|
Phase 1 | |
Completed |
NCT03202901 -
Accute Effect of B-Turmactive Both on Mild and Moderate Knee Pain on Healthy Volunteers
|
N/A | |
Completed |
NCT06206018 -
Patient-Reported Outcome Measures in Lower Extremity Rehabilitation Program PROM_R: Impact on Health Care
|
N/A | |
Completed |
NCT04543227 -
Opioid Laws and Pediatric Use
|
||
Completed |
NCT06078072 -
Biomaterials and Mesenchymal Stem/Stromal Cells in the Treatment of Knee Articular Surface Lesions
|
||
Completed |
NCT04956393 -
The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study
|
N/A | |
Recruiting |
NCT06451510 -
Knee Osteoarthritis in the Region of Norrbotten
|
||
Completed |
NCT04118023 -
7T MRI to Evaluate Cartilage Defects in the Knee
|
||
Completed |
NCT03486405 -
A Randomized Control Trial: Returning to Run After Injury
|
N/A | |
Recruiting |
NCT03858231 -
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
|
Phase 4 | |
Recruiting |
NCT02918734 -
Fixation of Patellar Tendon Grafts in Anterior Cruciate Ligament Reconstruction. Endobutton vs Metal Interference Screws
|
N/A | |
Suspended |
NCT02270905 -
Clinical Evaluation of dCELL® Meniscus for Partial Replacement of the Meniscus
|
N/A | |
Completed |
NCT01227694 -
Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis
|
Phase 1/Phase 2 | |
Completed |
NCT00991588 -
Clinical Outcome of Posterior Cruciate Ligament (PCL) Posterolateral Reconstruction
|