Knee Injuries Clinical Trial
— KneePRPOfficial title:
Does Post-Operative Intra-Articular Platelet Rich Plasma Injection Improve Meniscal Repair Outcomes
Verified date | April 2019 |
Source | Alexandria University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The investigator's hypothesis was that intra-articular knee injection with PRP in patients underwent arthroscopic meniscal repair and didn't receive intra-surgical PRP, may add beneficial effect on post-meniscal repair outcomes regarding pain, functional state of the operated knee as well as healing process.
Status | Completed |
Enrollment | 30 |
Est. completion date | March 20, 2018 |
Est. primary completion date | December 5, 2017 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 55 Years |
Eligibility |
Inclusion Criteria: - Patients aged 18-55 years - Complete meniscal tear in red-white zone done repaired - Surgery was done by by a single surgeon Exclusion Criteria: - Some systemic disorders, such as diabetes, autoimmune diseases, hematological disorders, cardiovascular diseases, infections - Local knee injuries other than meniscal injury - Patients receiving treatment with anticoagulants-anti-aggregates - Use of NSAIDs within 5 days before local PRP injection. |
Country | Name | City | State |
---|---|---|---|
Egypt | Rehab Abdelaal ELnemr | Alexandria |
Lead Sponsor | Collaborator |
---|---|
Alexandria University | University of Alexandria |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | knee Pain | visual analogue scale, a line 10cm long, zero represent no pain and 10 represent maximal pain, the patient is asked to put a mark that describe his pain | 3 months | |
Primary | Knee function | Knee injury and osteoarthritis outcome score, assesses five outcomes: pain, symptoms, activities of daily living, sport and recreation function, and knee-related quality of life. The KOOS's five patient-relevant dimensions are scored separately: Pain (nine items); Symptoms (seven items); ADL Function (17 items); Sport and Recreation Function (five items); Quality of Life (four items). A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included. Scores are transformed to a 0-100 scale, with zero representing extreme knee problems and 100 representing no knee problems | 3 months | |
Primary | meniscal healing process | by ultrasonography | 3 months | |
Secondary | knee pain | visual analogue scale, a line 10cm long, zero represent no pain and 10 represent maximal pain, the patient is asked to put a mark that describe his pain | 6 months | |
Secondary | knee function | Knee injury and osteoarthritis outcome score, assesses five outcomes: pain, symptoms, activities of daily living, sport and recreation function, and knee-related quality of life. The KOOS's five patient-relevant dimensions are scored separately: Pain (nine items); Symptoms (seven items); ADL Function (17 items); Sport and Recreation Function (five items); Quality of Life (four items). A Likert scale is used and all items have five possible answer options scored from 0 (No problems) to 4 (Extreme problems) and each of the five scores is calculated as the sum of the items included. Scores are transformed to a 0-100 scale, with zero representing extreme knee problems and 100 representing no knee problems | 6 months | |
Secondary | meniscal healing | by ultrasonography | 6 months |
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