Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound

Kidney Clinical Trial

Official title:

Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound

Clinical Trial Details — Status: Unknown status

Administrative data

• NCT number: NCT00631553
• Other study ID #: 12014
• Status: Unknown status
• Phase: N/A
• First received: February 27, 2008
• Last updated: August 6, 2008
• Start date: June 2006
• Est. completion date: December 2009

Study information

• Verified date: August 2008
• Source: University of Virginia
• Contact: Kambiz Kalantarinia, MD
• Phone: 434 924 5125
• Email: kk6c[@]virginia.edu
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine if contrast enhanced ultrasound (CEU) using microbubbles, is useful in assessing changes in kidney blood flow.

Recruitment information / eligibility

• Status: Unknown status
• Enrollment: 20
• Est. completion date: December 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Healthy adults

• Males and females

• Ages 18-65 years old

Exclusion Criteria:

• Pregnancy or lactation

• H/o kidney disease

• H/o congestive heart failure, ischemic heart disease, severe pulmonary disease or allergy to the drug

• H/o any cardiovascular disease

• Abnormal liver function (liver function tests out of specified ranges)

• Screening urinalysis which indicates infection or inflammation

• Taking regular medications (except for over-the-counter vitamins or hormonal contraceptives.)

• Taking supplements, like protein shakes

• Unwilling or unable to eat chicken (used as protein meal)

Related Conditions & MeSH terms

• Kidney

Intervention

Drug:
• perflutren lipid microspheres
1.3 ml in 30 ml of saline, infused into vein at 2ml / min and titrated for optimal image quality (not to exceed 10 ml/ min at any time).

Locations

Country	Name	City	State
United States	University of Virginia Health System	Charlottesville	Virginia

Sponsors (2)

Lead Sponsor	Collaborator
University of Virginia	National Institutes of Health (NIH)

Country where clinical trial is conducted

United States,