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Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients

Kidney Transplant Rejection Clinical Trial

Official title:
AT-1501-K209: BESTOW-EXTENSION: A Phase 2, Multicenter, Open-Label Extension Study to Evaluate the Long-Term Safety and Efficacy of Tegoprubart in Kidney Transplant Recipients

Clinical Trial Summary

This study will evaluate the long term safety and efficacy of AT-1501 (tegoprubart) compared with tacrolimus in patients undergoing kidney transplantation.

Clinical Trial Description

This is a multicenter, open-label, active control extension study to assess the long-term safety and efficacy of AT-1501 (tegoprubart) compared with tacrolimus in the preservation of allograft function after kidney transplantation. The number of patients enrolled for OLE study will depend on the enrollment in the Parent studies. To be eligible for participation in this study, participants must have completed a designated Parent study. Participants in this study will continue the treatment regimen they were receiving in the Parent study. Dose regimens will include either AT-1501 (tegoprubart) or tacrolimus. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06126380
Study type Interventional
Source Eledon Pharmaceuticals
Contact
Status Enrolling by invitation
Phase Phase 2
Start date October 25, 2023
Completion date December 2029
View Details
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