Kidney Transplantation Clinical Trial
Official title:
Performances of Estimated Glomerular Filtration Rate Equations in Kidney Transplant Recipients
NCT number | NCT05229939 |
Other study ID # | KRSeGFR2021 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | January 1, 2000 |
Est. completion date | January 1, 2021 |
Verified date | August 2022 |
Source | Paris Translational Research Center for Organ Transplantation |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Accurate estimation of the glomerular filtration rate (GFR) is crucial for the management of kidney recipients, since it is the most predictive parameter of allograft failure that drives patient monitoring and decision-making. Standard and recent race-free GFR equations have been developed in native kidneys, but their performances in transplant kidney population remains unknown. We aimed at developing a kidney-transplant-specific GFR equation, and comparing its performance to standard GFR equations.
Status | Completed |
Enrollment | 11412 |
Est. completion date | January 1, 2021 |
Est. primary completion date | January 1, 2021 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Living or deceased donor kidney recipient transplanted between 01/01/2000 and 01/01/2021. - Men or women over 18 years of age. - Written informed consent at the time of transplantation for the center database. Exclusion Criteria: • Combined transplantation |
Country | Name | City | State |
---|---|---|---|
Croatia | Department of Nephrology, Arterial Hypertension, Dialysis and Transplantation, University Hospital Centre Zagreb, School of Medicine, University of Zagreb | Zagreb | |
France | Department of Transplantation, Nephrology and Clinical Immunology, Hospices Civils de Lyon | Lyon | |
France | Department of Nephrology, Centre Hospitalier Universitaire, Montpellier | Montpellier | |
France | Kidney Transplant Department, Necker Hospital, Assistance Publique - Hôpitaux de Paris | Paris | |
France | Kidney Transplant Department, Saint-Louis Hospital, Assistance Publique - Hôpitaux de Paris | Paris | |
France | Kidney Transplant Department, Tenon Hospital, Assistance Publique - Hôpitaux de Paris | Paris | |
France | Nephrology, Dialysis and Renal Transplantation Department, Hôpital Nord, CHU de Saint-Etienne, Jean Monnet University, Université de Lyon | Saint-Étienne | |
France | Department of Nephrology and Organ Transplantation, CHU Rangueil | Toulouse | |
Italy | Istituto di Ricerche Farmacologiche Mario Negri IRCCS | Bergamo | |
United States | William J. von Liebig Centre for Transplantation and Clinical Regeneration, Mayo Clinic | Rochester | Minnesota |
Lead Sponsor | Collaborator |
---|---|
Paris Translational Research Center for Organ Transplantation |
United States, Croatia, France, Italy,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Measured glomerular filtration rate (mGFR) | Isotopic measurements of GFR | Up to 15 years after kidney transplantation |
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