Kidney Transplantation Clinical Trial
Official title:
Prediction of Medication Compliance Following Renal Transplantation
The purpose of this study is to quantitate pre-transplant medication compliance, dialysis
compliance, and related psychological variables, and then examine their validity as
predictors of post-transplant noncompliant behaviors and clinically relevant outcomes (acute
rejection, graft loss, or death).
Hypothesis: Noncompliance with pre-transplant medication or with the dialysis prescription,
and specific psychological variables predict similarly noncompliant behaviors after
transplantation.
Status | Completed |
Enrollment | 30 |
Est. completion date | November 2014 |
Est. primary completion date | November 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 14 Years and older |
Eligibility |
Inclusion Criteria: - Adult hemodialysis patients in renal transplant evaluation - Able to read test forms - Responsible for their own medications Exclusion Criteria: - Patients with a major risk of recurrent primary renal disease, e.g. hemolytic uremic syndrome, oxalosis, membranoproliferative glomerulonephritis type II, focal segmental glomerulosclerosis with nephrotic syndrome. - Patients with active psychosis - Patients who do not speak English. - Patients who live and will be followed outside the United States, except Canada. - Patients who are physically unable to open the Medication Event Monitoring System (MEMS) cap. - Patients who are not responsible for taking their own medications, e.g. living in a medical care facility. - Patients who are younger than 14 years old - Patients who will receive an extra renal organ (except pancreas), either simultaneously or previously. |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | University of Minnesota | Minneapolis | Minnesota |
Lead Sponsor | Collaborator |
---|---|
University of Minnesota - Clinical and Translational Science Institute | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Prediction of early medication adherence | Prediction of declining medication adherence during first three months post kidney transplantation. | 3 months | No |
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