Cryaoablation Assisted Partial Nephrectomy a Non Ischemic Approach — RCAPN  

Kidney Neoplasms Clinical Trial

Official title: Cryotherapy and Robotic Assisted Non Ischemic Nephron Sparring Surgery

Status Recruiting

Clinical Trial Summary

Patients with renal masses eligible to partial nephrectomy often require arterial ischemia to control or prevent blood loss during this surgical procedure. This study aims to determine the safety and efficacy of renal cryoablation at the tumor bed, as a substitute measure or technique vs total or selective arterial renal ischemia.

Clinical Trial Description

Nephron sparring surgery has emerged as the procedure of choice for most patients with renal tumors that are >2 cm and harbor a greater than 50% exophitic component. In order to decrease blood loss surgeons may: 1- interrupt blood flow to the kidney, completely or selectively; 2-Use diuretics such as mannitol to dehydrate the kidney; 3-Ice externally the kidney - in open procedures - to decrease metabolism during ischemia.

The emergence of robotic surgery triggered a shift in the the surgical approach to partial nephrectomy and is commonly employed. A fundamental drawback of this technique is represented on the lack of cold ischemia. However, warm ischemia is commonly employed and requires dissection of the renal pedicle, which by itself puts the kidney at risk of loss. ;

Related Conditions & MeSH terms

• Kidney Neoplasms

• NCT number: NCT05218811
• Study type: Interventional
• Source: Urological Research Network, LLC
• Contact: Eusebio J Luna, MD
• Phone: 3058227227
• Email: drluna@research.surgery
• Status: Recruiting
• Phase: N/A
• Start date: May 15, 2020
• Completion date: May 15, 2041