Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Kidney Injury Clinical Trial

Official title:

Analgesic Effectiveness of the Serratus-intercostal Plane Block Versus Quadratus Lumborum Block in Nephrectomy: Randomized Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04431388
• Other study ID #: CASVE-NM-20-434
• Secondary ID: 2020-000779-19
• Status: Completed
• Start date: June 1, 2021
• Est. completion date: December 1, 2023

Study information

• Verified date: March 2024
• Source: Hospital Medina del Campo
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Performing the nephrectomy by laparoscopy has decrease the incidence of postoperative pain, but there are still some patients who describe a severe pain after this surgery. Regional techniques allow a better recovery quality and adequate- managed pain control.

Description:

Adequate control of pain in patients with nephrectomy is a challenge for the anesthesiologist who must achieve an early recovery with minimal adverse effects. Within a multimodal strategy, the work hypothesis is based on comparing the analgesic efficacy of two regional techniques in patients undergoing nephrectomy, in terms of quality of postoperative recovery, pain control, absence of adverse effects and ease of performance.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 126
• Est. completion date: December 1, 2023
• Est. primary completion date: June 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• signature of informed consent

• age > 18 years

• ASA risk scale < IV

• Scheduled to nephrectomy.

Exclusion Criteria:

• Patients with cognitive impairment or inability to sign informed consent,

• Refused to participate

• Hypersensitivity to the drugs used

• contraindication of regional technique (coagulopathy, infection)

• history of chronic pain.

Related Conditions & MeSH terms

• Kidney Injury

Intervention

Device:
• ultrasound device
We performe a differnt analgesic techniques to know if some of then are better

Drug:
• Levobupivacaine
using the same AL

Locations

Country	Name	City	State
Spain	María Teresa Fernandez	Valladolid	VA

Sponsors (1)

Lead Sponsor	Collaborator
Hospital Medina del Campo

Country where clinical trial is conducted

Spain, 

References & Publications (4)

Corso RM, Piraccini E, Sorbello M, Bellantonio D, Tedesco M. Transmuscular quadratus lumborum block versus serratus-intercostal interfascial plane block: the game has just begun. Minerva Anestesiol. 2018 Jul;84(7):873-874. doi: 10.23736/S0375-9393.18.12849-5. Epub 2018 Mar 27. No abstract available. — View Citation

Corso RM, Piraccini E, Sorbello M, Bellantonio D, Tedesco M. Ultrasound-guided transmuscular quadratus lumborum block for perioperative analgesia in open nephrectomy. Minerva Anestesiol. 2017 Dec;83(12):1334-1335. doi: 10.23736/S0375-9393.17.12167-X. Epub 2017 Jul 5. No abstract available. — View Citation

Fernandez Martin MT, Lopez Alvarez S, Fajardo Perez M, Perez Herrero M. Serratus-intercostal interfascial plane block: alternative analgesia for open nephrectomy? Minerva Anestesiol. 2018 Jul;84(7):872-873. doi: 10.23736/S0375-9393.18.12808-2. Epub 2018 Feb 22. No abstract available. — View Citation

Fernandez Martin MT, Lopez Alvarez S, Perez Herrero MA. Serratus-intercostal interfascial block as an opioid-saving strategy in supra-umbilical open surgery. Rev Esp Anestesiol Reanim (Engl Ed). 2018 Oct;65(8):456-460. doi: 10.1016/j.redar.2018.03.007. Epub 2018 May 20. English, Spanish. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	control	Third outcome will be to know if both blocks control pain better than control group	"24 hours"
Primary	pain control and quality life.Numeric rating scale (NRS)	To assess whether SIPB is superior in pain control	"24 postoperative hours"
Primary	QoR15	Postoperative quality recovery	"24hours"
Secondary	Opioids consumption	Second outcomes was to know the consumption of intaoperative fentanyl and postoperative morphine and their side effects	"48 hours"
Secondary	Side effects	We assessed the side effects of opioids	"24hours"