I USE LR in the ED

Kidney Injury Clinical Trial

Official title:

Intermountain Utah Study Evaluating the Implementation of Lactated Ringers as Standard Resuscitation Fluid Starting in Emergency Department

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03807648
• Other study ID #: 1050984
• Status: Completed
• Start date: December 20, 2018
• Est. completion date: January 31, 2020

Study information

• Verified date: February 2020
• Source: Intermountain Health Care, Inc.
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To study the difference in mortality and major adverse kidney events during and after treatment in the emergency department with intravenous fluids per standard of care at 30 days before and after the system-wide implementation.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 200000
• Est. completion date: January 31, 2020
• Est. primary completion date: December 31, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Adult patients (=18 years) receiving a minimum of 1000ml of intravenous fluids starting in the emergency department per standard of care

Exclusion Criteria:

• Patients aged =17 years

• Previously enrolled patients with >1 ED admission within the 30-day follow-up period

Related Conditions & MeSH terms

• Kidney Injury

Intervention

Other:
• Data Inclusion
Patients in this group will be included in the project

Locations

Country	Name	City	State
United States	Intermountain Medical Center	Murray	Utah

Sponsors (1)

Lead Sponsor	Collaborator
Intermountain Health Care, Inc.

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of participants with major Adverse Kidney Events	death from any cause, new renal replacement therapy or persistent renal dysfunction	within 30 days or at hospital discharge
Primary	LR IV Fluids administered	Proportion of LR IV fluids following implementation	Through study completion (an average of 1 year)
Secondary	Rate of hospital admission and readmission		Within 30 days of initial ED encounter
Secondary	Cost	Direct costs of ED care and hospitalization	Through study completion (an average of 1 year)